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Beckman, Joseph S
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Amyotrophic Lateral Sclerosis
Williams JR
,
Trias E
,
Beilby PR
,
Lopez NI
,
Labut EM
,
C Bradford S
,
Roberts BR
,
McAllum EJ
,
Crouch PJ
,
Rhoads TW
et al.
. 2016.
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
.
Neurobiol Dis. 89:1-9.
Kovacs M
,
Trias E
,
Varela V
,
Ibarburu S
,
Beckman JS
,
Moura IC
,
Hermine O
,
King PH
,
Si Y
,
Kwon Y
et al.
. 2019.
CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.
.
Int J Mol Sci. 20(16)
Beckman JS
,
Esétvez AG
,
Barbeito L
,
Crow JP
. 2002.
CCS knockout mice establish an alternative source of copper for SOD in ALS.
.
Free Radic Biol Med. 33(10):1433-5.
Robinson KM
,
Janes MS
,
Beckman JS
. 2008.
The selective detection of mitochondrial superoxide by live cell imaging.
.
Nat Protoc. 3(6):941-7.
Kim MJin
,
Vargas MR
,
Harlan BA
,
Killoy KM
,
Ball LE
,
Comte-Walters S
,
Gooz M
,
Yamamoto Y
,
Beckman JS
,
Barbeito L
et al.
. 2018.
Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.
.
Antioxid Redox Signal. 28(18):1587-1602.
Leinweber B
,
Barofsky E
,
Barofsky DF
,
Ermilov V
,
Nylin K
,
Beckman JS
. 2004.
Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.
.
Free Radic Biol Med. 36(7):911-8.
Trias E
,
Ibarburu S
,
Barreto-Núñez R
,
Babdor J
,
Maciel TT
,
Guillo M
,
Gros L
,
Dubreuil P
,
Díaz-Amarilla P
,
Cassina P
et al.
. 2016.
Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.
.
J Neuroinflammation. 13(1):177.
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
Amino Acid Substitution
Leinweber B
,
Barofsky E
,
Barofsky DF
,
Ermilov V
,
Nylin K
,
Beckman JS
. 2004.
Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.
.
Free Radic Biol Med. 36(7):911-8.
Amino Acid Sequence
Fort KL
,
Cramer CN
,
Voinov VG
,
Vasil'ev YV
,
Lopez NI
,
Beckman JS
,
Heck AJR
. 2018.
Exploring ECD on a Benchtop Q Exactive Orbitrap Mass Spectrometer.
.
J Proteome Res. 17(2):926-933.
Voinov VG
,
Hoffman PD
,
Bennett SE
,
Beckman JS
,
Barofsky DF
. 2015.
Electron Capture Dissociation of Sodium-Adducted Peptides on a Modified Quadrupole/Time-of-Flight Mass Spectrometer.
.
J Am Soc Mass Spectrom. 26(12):2096-104.
Administration, Oral
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Acetylation
Leinweber B
,
Barofsky E
,
Barofsky DF
,
Ermilov V
,
Nylin K
,
Beckman JS
. 2004.
Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.
.
Free Radic Biol Med. 36(7):911-8.
Acetophenones
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
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