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Faculty and Staff
Our Research
Micronutrient Information
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Stevens, Jan F
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Humans
Langley BO
,
Ryan JJoan
,
Phipps J
,
Buttolph L
,
Bray B
,
Aslan JE
,
Metz TO
,
Stevens JF
,
Bradley R
. 2022.
Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.
.
Trials. 23(1):885.
Axton ER
,
Hardardt EA
,
Stevens JF
. 2016.
Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.
Khorani M
,
Bobe G
,
Matthews DG
,
Magana AAlcazar
,
Caruso M
,
Gray NE
,
Quinn JF
,
Stevens JF
,
Soumyanath A
,
Maier CS
. 2022.
The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways.
.
J Alzheimers Dis. 85(4):1601-1619.
Legette LC
,
Karnpracha C
,
Reed RL
,
Choi J
,
Bobe G
,
J Christensen M
,
Rodriguez-Proteau R
,
Purnell JQ
,
Stevens JF
. 2014.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
.
Mol Nutr Food Res. 58(2):248-55.
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Magana AAlcazar
,
Vaswani A
,
Brown KS
,
Jiang Y
,
Alam MNure
,
Caruso M
,
Lak P
,
Cheong P
,
Gray NE
,
Quinn JF
et al.
. 2024.
Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.
.
Molecules. 29(4)
Kuiper HC
,
Langsdorf BL
,
Miranda CL
,
Joss J
,
Jubert C
,
Mata JE
,
Stevens JF
. 2010.
Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study.
.
Free Radic Biol Med. 48(1):65-72.
Kuiper HC
,
Bruno RS
,
Traber MG
,
Stevens JF
. 2011.
Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.
.
Free Radic Biol Med. 50(7):848-53.
Stevens JF
,
Page JE
. 2004.
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
.
Phytochemistry. 65(10):1317-30.
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Bouranis JA
,
Beaver LM
,
Jiang D
,
Choi J
,
Wong CP
,
Davis EW
,
Williams DE
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2022.
Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.
.
Nutrients. 15(1)
Humulus
Lela L
,
Ponticelli M
,
Carlucci V
,
Stevens JF
,
Faraone I
,
Tzvetkov NT
,
Milella L
. 2024.
Insight into the Interaction of L. Specialized Metabolites and Gastrointestinal Bitter Taste Receptors: Study in STC-1 Cells and Molecular Docking.
.
J Nat Prod. 87(8):2021-2033.
Stevens JF
,
Page JE
. 2004.
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
.
Phytochemistry. 65(10):1317-30.
Miranda CL
,
Elias VD
,
Hay JJ
,
Choi J
,
Reed RL
,
Stevens JF
. 2016.
Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.
.
Arch Biochem Biophys. 599:22-30.
Ellinwood DC
,
El-Mansy MF
,
Plagmann LS
,
Stevens JF
,
Maier CS
,
Gombart AF
,
Blakemore PR
. 2017.
Total synthesis of [ C] -, [ C] -, and [ C] -isotopomers of xanthohumol, the principal prenylflavonoid from hops.
.
J Labelled Comp Radiopharm. 60(14):639-648.
Legette LC
,
Karnpracha C
,
Reed RL
,
Choi J
,
Bobe G
,
J Christensen M
,
Rodriguez-Proteau R
,
Purnell JQ
,
Stevens JF
. 2014.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
.
Mol Nutr Food Res. 58(2):248-55.
Hydrazines
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Hydrolysis
Kubglomsong S
,
Theerakulkait C
,
Reed RL
,
Yang L
,
Maier CS
,
Stevens JF
. 2018.
Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.
.
J Agric Food Chem. 66(31):8346-8354.
Wattanasiritham L
,
Theerakulkait C
,
Wickramasekara S
,
Maier CS
,
Stevens JF
. 2016.
Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein.
.
Food Chem. 192:156-62.
Hypoglycemic Agents
Legette LC
,
Karnpracha C
,
Reed RL
,
Choi J
,
Bobe G
,
J Christensen M
,
Rodriguez-Proteau R
,
Purnell JQ
,
Stevens JF
. 2014.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
.
Mol Nutr Food Res. 58(2):248-55.
Hypoxia-Inducible Factor 1
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Inactivation, Metabolic
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Inflammation
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Langley BO
,
Ryan JJoan
,
Phipps J
,
Buttolph L
,
Bray B
,
Aslan JE
,
Metz TO
,
Stevens JF
,
Bradley R
. 2022.
Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.
.
Trials. 23(1):885.
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