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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Flow Cytometry
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Food Analysis
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.
.
Nutrients. 9(12)
Free Radical Scavengers
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Free Radicals
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Fructose
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Fruit
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Fungal Proteins
Yilmazer-Musa M
,
Griffith AM
,
Michels AJ
,
Schneider E
,
Frei B
. 2012.
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.
.
J Agric Food Chem. 60(36):8924-9.
Gas Chromatography-Mass Spectrometry
Taylor AW
,
Bruno RS
,
Frei B
,
Traber MG
. 2006.
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.
.
Anal Biochem. 350(1):41-51.
Gene Expression
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Gene Expression Profiling
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Gene Expression Regulation
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Zhang W-J
,
Wei H
,
Frei B
. 2009.
Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo.
.
Free Radic Biol Med. 46(6):791-8.
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Gene Expression Regulation, Enzymologic
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Genetic Variation
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
Glucose Intolerance
Higdon JV
,
Frei B
. 2006.
Coffee and health: a review of recent human research.
.
Crit Rev Food Sci Nutr. 46(2):101-23.
Glutamate-Cysteine Ligase
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Glutathione
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
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