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Ho, Emily
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Inflammation
Wong CP
,
Rinaldi NA
,
Ho E
. 2015.
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
.
Mol Nutr Food Res. 59(5):991-9.
Inhibitor of Apoptosis Proteins
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Insulin
Beaver LM
,
Nkrumah-Elie YM
,
Truong L
,
Barton CL
,
Knecht AL
,
Gonnerman GD
,
Wong CP
,
Tanguay RL
,
Ho E
. 2017.
Adverse effects of parental zinc deficiency on metal homeostasis and embryonic development in a zebrafish model.
.
J Nutr Biochem. 43:78-87.
Intercellular Adhesion Molecule-1
Wong CP
,
Rinaldi NA
,
Ho E
. 2015.
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
.
Mol Nutr Food Res. 59(5):991-9.
Interleukin-6
Wong CP
,
Rinaldi NA
,
Ho E
. 2015.
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
.
Mol Nutr Food Res. 59(5):991-9.
Intestinal Mucosa
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Intestinal Neoplasms
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Intestinal Polyps
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Isothiocyanates
Nian H
,
Delage B
,
Ho E
,
Dashwood RH
. 2009.
Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.
.
Environ Mol Mutagen. 50(3):213-21.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Beaver LM
,
Kuintzle R
,
Buchanan A
,
Wiley MW
,
Glasser ST
,
Wong CP
,
Johnson GS
,
Chang JH
,
Löhr CV
,
Williams DE
et al.
. 2017.
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.
.
J Nutr Biochem. 42:72-83.
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Atwell LL
,
Zhang Z
,
Mori M
,
Farris P
,
Vetto JT
,
Naik AM
,
Oh KY
,
Thuillier P
,
Ho E
,
Shannon J
. 2015.
Sulforaphane Bioavailability and Chemopreventive Activity in Women Scheduled for Breast Biopsy.
.
Cancer Prev Res (Phila). 8(12):1184-1191.
Myzak MC
,
Hardin K
,
Wang R
,
Dashwood RH
,
Ho E
. 2006.
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
.
Carcinogenesis. 27(4):811-9.
Abbas A
,
J Hall A
,
Patterson WL
,
Ho E
,
Hsu A
,
Al-Mulla F
,
Georgel PT
. 2016.
Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.
.
Biochem Cell Biol. 94(1):71-81.
Kaplan-Meier Estimate
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Lung
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Lung Neoplasms
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Lysine
Abbas A
,
J Hall A
,
Patterson WL
,
Ho E
,
Hsu A
,
Al-Mulla F
,
Georgel PT
. 2016.
Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.
.
Biochem Cell Biol. 94(1):71-81.
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