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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Humans
Zhang WJian
,
Stocker R
,
McCall MR
,
Forte TM
,
Frei B
. 2002.
Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells.
.
Atherosclerosis. 165(2):241-9.
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Lotito SB
,
Frei B
. 2004.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
.
Free Radic Biol Med. 36(2):201-11.
Blumberg JB
,
Frei B
,
Fulgoni VL
,
Weaver CM
,
Zeisel SH
. 2017.
Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.
.
Nutrients. 9(12)
Lotito SB
,
Zhang W-J
,
Yang CS
,
Crozier A
,
Frei B
. 2011.
Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.
.
Free Radic Biol Med. 51(2):454-63.
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Zhang W-J
,
Wei H
,
Hagen T
,
Frei B
. 2007.
Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.
.
Proc Natl Acad Sci U S A. 104(10):4077-82.
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Higdon JV
,
Frei B
. 2006.
Coffee and health: a review of recent human research.
.
Crit Rev Food Sci Nutr. 46(2):101-23.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Michels AJ
,
Frei B
. 2013.
Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.
.
Nutrients. 5(12):5161-92.
Higdon JV
,
Frei B
. 2005.
Is there a gender difference in the effect of antioxidants on cancer risk?
Br J Nutr. 94(2):139-40.
Traber MG
,
Frei B
,
Beckman JS
. 2008.
Vitamin E revisited: do new data validate benefits for chronic disease prevention?
Curr Opin Lipidol. 19(1):30-8.
Taylor AW
,
Bruno RS
,
Frei B
,
Traber MG
. 2006.
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.
.
Anal Biochem. 350(1):41-51.
Hydrogen Peroxide
Frei B
,
Lawson S
. 2008.
Vitamin C and cancer revisited.
.
Proc Natl Acad Sci U S A. 105(32):11037-8.
Zhu B-Z
,
Zhao H-T
,
Kalyanaraman B
,
Frei B
. 2002.
Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study.
.
Free Radic Biol Med. 32(5):465-73.
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Hydroxyl Radical
Zhu B-Z
,
Zhao H-T
,
Kalyanaraman B
,
Frei B
. 2002.
Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study.
.
Free Radic Biol Med. 32(5):465-73.
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Hypochlorous Acid
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
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