Linus Pauling Institute

Zhang WJian, Stocker R, McCall MR, Forte TM, Frei B.  2002.  Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells.. Atherosclerosis. 165(2):241-9.

Lotito SB, Frei B.  2006.  Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon? Free Radic Biol Med. 41(12):1727-46.

Li C, Zhang W-J, Choi J, Frei B.  2016.  Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.. Redox Biol. 9:220-228.

Lotito SB, Frei B.  2004.  Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.. Free Radic Biol Med. 36(2):201-11.

Zhang W-J, Frei B.  2002.  Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.. Cardiovasc Res. 55(4):820-9.

Blumberg JB, Frei B, Fulgoni VL, Weaver CM, Zeisel SH.  2017.  Contribution of Dietary Supplements to Nutritional Adequacy in Various Adult Age Groups.. Nutrients. 9(12)

Lotito SB, Zhang W-J, Yang CS, Crozier A, Frei B.  2011.  Metabolic conversion of dietary flavonoids alters their anti-inflammatory and antioxidant properties.. Free Radic Biol Med. 51(2):454-63.

Higdon JV, Frei B.  2003.  Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.. Crit Rev Food Sci Nutr. 43(1):89-143.

Mastaloudis A, Yu T-W, O'Donnell RP, Frei B, Dashwood RH, Traber MG.  2004.  Endurance exercise results in DNA damage as detected by the comet assay.. Free Radic Biol Med. 36(8):966-75.

Li C, Zhang W-J, Frei B.  2016.  Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.. Redox Biol. 9:104-113.

Visioli F, Smith A, Zhang W, Keaney JF, Hagen T, Frei B.  2002.  Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.. Redox Rep. 7(4):223-7.

Zhang W-J, Wei H, Hagen T, Frei B.  2007.  Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.. Proc Natl Acad Sci U S A. 104(10):4077-82.

Li L, Frei B.  2009.  Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.. Arterioscler Thromb Vasc Biol. 29(5):732-8.

Higdon JV, Frei B.  2006.  Coffee and health: a review of recent human research.. Crit Rev Food Sci Nutr. 46(2):101-23.

Lotito SB, Frei B.  2006.  Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.. J Biol Chem. 281(48):37102-10.

Michels AJ, Frei B.  2013.  Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.. Nutrients. 5(12):5161-92.

Higdon JV, Frei B.  2005.  Is there a gender difference in the effect of antioxidants on cancer risk? Br J Nutr. 94(2):139-40.

Traber MG, Frei B, Beckman JS.  2008.  Vitamin E revisited: do new data validate benefits for chronic disease prevention? Curr Opin Lipidol. 19(1):30-8.

Taylor AW, Bruno RS, Frei B, Traber MG.  2006.  Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.. Anal Biochem. 350(1):41-51.

Frei B, Lawson S.  2008.  Vitamin C and cancer revisited.. Proc Natl Acad Sci U S A. 105(32):11037-8.

Zhu B-Z, Zhao H-T, Kalyanaraman B, Frei B.  2002.  Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study.. Free Radic Biol Med. 32(5):465-73.

Zhu B-Z, Antholine WE, Frei B.  2002.  Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.. Free Radic Biol Med. 32(12):1333-8.

Zhu B-Z, Zhao H-T, Kalyanaraman B, Frei B.  2002.  Metal-independent production of hydroxyl radicals by halogenated quinones and hydrogen peroxide: an ESR spin trapping study.. Free Radic Biol Med. 32(5):465-73.

Zhu B-Z, Antholine WE, Frei B.  2002.  Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.. Free Radic Biol Med. 32(12):1333-8.

Zhu B-Z, Carr AC, Frei B.  2002.  Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.. FEBS Lett. 532(1-2):80-4.