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Faculty and Staff
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Toxicokinetics
Maier MLVermilli
,
Siddens LK
,
Pennington JM
,
Uesugi SL
,
Tilton SC
,
Vertel EA
,
Anderson KA
,
Tidwell LG
,
Ognibene TJ
,
Turteltaub KW
et al.
. 2023.
Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.
.
Toxicol Appl Pharmacol. 460:116377.
Maier MLVermilli
,
Siddens LK
,
Pennington JM
,
Uesugi SL
,
Labut EM
,
Vertel EA
,
Anderson KA
,
Tidwell LG
,
Tilton SC
,
Ognibene TJ
et al.
. 2023.
Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.
.
Chem Biol Interact. 382:110608.
Trans-Activators
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.
.
Carcinogenesis. 24(2):263-7.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Blum CA
,
Xu M
,
Orner GA
,
Fong AT
,
Bailey GS
,
Stoner GD
,
Horio DT
,
Dashwood RH
. 2001.
beta-Catenin mutation in rat colon tumors initiated by 1,2-dimethylhydrazine and 2-amino-3-methylimidazo[4,5-f]quinoline, and the effect of post-initiation treatment with chlorophyllin and indole-3-carbinol.
.
Carcinogenesis. 22(2):315-20.
Dashwood W-M
,
Orner GA
,
Dashwood RH
. 2002.
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
.
Biochem Biophys Res Commun. 296(3):584-8.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Transcription Factor 7-Like 2 Protein
Dashwood W-M
,
Orner GA
,
Dashwood RH
. 2002.
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
.
Biochem Biophys Res Commun. 296(3):584-8.
Transcription Factors
Dashwood W-M
,
Orner GA
,
Dashwood RH
. 2002.
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
.
Biochem Biophys Res Commun. 296(3):584-8.
Transcriptional Activation
Dashwood W-M
,
Orner GA
,
Dashwood RH
. 2002.
Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.
.
Biochem Biophys Res Commun. 296(3):584-8.
Trout
Bailey GS
,
Reddy AP
,
Pereira CB
,
Harttig U
,
Baird W
,
Spitsbergen JM
,
Hendricks JD
,
Orner GA
,
Williams DE
,
Swenberg JA
. 2009.
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.
.
Chem Res Toxicol. 22(7):1264-76.
United States
Lee BY
,
Ordovás JM
,
Parks EJ
,
Anderson CAM
,
Barabási A-L
,
Clinton SK
,
de la Haye K
,
Duffy VB
,
Franks PW
,
Ginexi EM
et al.
. 2022.
Research gaps and opportunities in precision nutrition: an NIH workshop report.
.
Am J Clin Nutr. 116(6):1877-1900.
Vitamins
Bredefeld C
,
M Hussain M
,
Averna M
,
Black DD
,
Brin MF
,
Burnett JR
,
Charrière S
,
Cuerq C
,
Davidson NO
,
Deckelbaum RJ
et al.
. 2022.
Guidance for the diagnosis and treatment of hypolipidemia disorders.
.
J Clin Lipidol. 16(6):797-812.
Weight Gain
Beaver LM
,
Song Y
,
Philbrick KA
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Ho E
,
Iwaniec UT
. 2023.
Severe Zinc Deficiency Impairs Accrual of Bone in Rapidly Growing Rats That Is Partially Corrected Following Short-term Zinc Repletion.
.
Biol Trace Elem Res. 201(8):3834-3849.
Xanthophylls
Neufeld LM
,
Ho E
,
Obeid R
,
Tzoulis C
,
Green M
,
Huber LG
,
Stout M
,
Griffiths JC
. 2023.
Advancing nutrition science to meet evolving global health needs.
.
Eur J Nutr. 62(Suppl 1):1-16.
Young Adult
Hummel JM
,
Madeen EP
,
Siddens LK
,
Uesugi SL
,
McQuistan T
,
Anderson KA
,
Turteltaub KW
,
Ognibene TJ
,
Bench G
,
Krueger SK
et al.
. 2018.
Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.
.
Food Chem Toxicol. 115:136-147.
Zinc
Beaver LM
,
Song Y
,
Philbrick KA
,
Wong CP
,
Olson DA
,
Branscum AJ
,
Turner RT
,
Ho E
,
Iwaniec UT
. 2023.
Severe Zinc Deficiency Impairs Accrual of Bone in Rapidly Growing Rats That Is Partially Corrected Following Short-term Zinc Repletion.
.
Biol Trace Elem Res. 201(8):3834-3849.
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