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Found 582 results
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Williams, David E
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Isotope Labeling
Harper TA
,
Morré J
,
Lauer FT
,
McQuistan TJ
,
Hummel JM
,
Burchiel SW
,
Williams DE
. 2015.
Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.
.
Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Kaplan-Meier Estimate
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Kidney
Larsen-Su SA
,
Krueger SK
,
Yueh MFei
,
Pereira CB
,
Williams DE
. 2002.
Developmental regulation of flavin-containing monooxygenase form 1 in the liver and kidney of fetal and neonatal rabbits.
.
Biochem Pharmacol. 63(7):1353-9.
Kinetics
Siddens LK
,
Henderson MC
,
VanDyke JE
,
Williams DE
,
Krueger SK
. 2008.
Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.
.
Biochem Pharmacol. 75(2):570-9.
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Liver
Traber MG
,
Siddens LK
,
Leonard SW
,
Schock B
,
Gohil K
,
Krueger SK
,
Cross CE
,
Williams DE
. 2005.
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
.
Free Radic Biol Med. 38(6):773-85.
Bailey GS
,
Reddy AP
,
Pereira CB
,
Harttig U
,
Baird W
,
Spitsbergen JM
,
Hendricks JD
,
Orner GA
,
Williams DE
,
Swenberg JA
. 2009.
Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.
.
Chem Res Toxicol. 22(7):1264-76.
Tilton SC
,
Givan SA
,
Pereira CB
,
Bailey GS
,
Williams DE
. 2006.
Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.
.
Toxicol Sci. 90(1):61-72.
Williams DE
. 2012.
The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
.
Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Larsen-Su SA
,
Krueger SK
,
Yueh MFei
,
Pereira CB
,
Williams DE
. 2002.
Developmental regulation of flavin-containing monooxygenase form 1 in the liver and kidney of fetal and neonatal rabbits.
.
Biochem Pharmacol. 63(7):1353-9.
Harper TA
,
Morré J
,
Lauer FT
,
McQuistan TJ
,
Hummel JM
,
Burchiel SW
,
Williams DE
. 2015.
Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.
.
Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Siddens LK
,
Henderson MC
,
VanDyke JE
,
Williams DE
,
Krueger SK
. 2008.
Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.
.
Biochem Pharmacol. 75(2):570-9.
Liver Neoplasms
Simonich MT
,
Egner PA
,
Roebuck BD
,
Orner GA
,
Jubert C
,
Pereira C
,
Groopman JD
,
Kensler TW
,
Dashwood RH
,
Williams DE
et al.
. 2007.
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
.
Carcinogenesis. 28(6):1294-302.
Liver Neoplasms, Experimental
Williams DE
. 2012.
The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
.
Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Tilton SC
,
Givan SA
,
Pereira CB
,
Bailey GS
,
Williams DE
. 2006.
Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.
.
Toxicol Sci. 90(1):61-72.
Lung
Siddens LK
,
Henderson MC
,
VanDyke JE
,
Williams DE
,
Krueger SK
. 2008.
Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.
.
Biochem Pharmacol. 75(2):570-9.
Harper TA
,
Morré J
,
Lauer FT
,
McQuistan TJ
,
Hummel JM
,
Burchiel SW
,
Williams DE
. 2015.
Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.
.
Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Krueger SK
,
Martin SR
,
Yueh M-F
,
Pereira CB
,
Williams DE
. 2002.
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.
.
Drug Metab Dispos. 30(1):34-41.
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Lung Neoplasms
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Macaca mulatta
Krueger SK
,
Martin SR
,
Yueh M-F
,
Pereira CB
,
Williams DE
. 2002.
Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.
.
Drug Metab Dispos. 30(1):34-41.
Magnesium
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Male
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
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