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Faculty and Staff
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Stevens, Jan F
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Mice
Kirkwood JS
,
Miranda CL
,
Bobe G
,
Maier CS
,
Stevens JF
. 2016.
18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.
.
PLoS One. 11(6):e0157118.
Johnson LA
,
Zuloaga KL
,
Kugelman TL
,
Mader KS
,
Morré JT
,
Zuloaga DG
,
Weber S
,
Marzulla T
,
Mulford A
,
Button D
et al.
. 2016.
Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.
.
EBioMedicine. 3:26-42.
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Mice, Inbred C57BL
Kundu P
,
Paraiso IL
,
Choi J
,
Miranda CL
,
Kioussi C
,
Maier CS
,
Bobe G
,
Stevens JF
,
Raber J
. 2022.
Xanthohumol improves cognition in farnesoid X receptor-deficient mice on a high-fat diet.
.
Dis Model Mech. 15(11)
Logan IE
,
Shulzhenko N
,
Sharpton TJ
,
Bobe G
,
Liu K
,
Nuss S
,
Jones ML
,
Miranda CL
,
Vasquez-Perez S
,
Pennington JM
et al.
. 2021.
Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
.
Mol Nutr Food Res. 65(21):e2100389.
Mice, Obese
Logan IE
,
Shulzhenko N
,
Sharpton TJ
,
Bobe G
,
Liu K
,
Nuss S
,
Jones ML
,
Miranda CL
,
Vasquez-Perez S
,
Pennington JM
et al.
. 2021.
Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
.
Mol Nutr Food Res. 65(21):e2100389.
Mice, Transgenic
Khorani M
,
Bobe G
,
Matthews DG
,
Magana AAlcazar
,
Caruso M
,
Gray NE
,
Quinn JF
,
Stevens JF
,
Soumyanath A
,
Maier CS
. 2022.
The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways.
.
J Alzheimers Dis. 85(4):1601-1619.
Microbiota
Langley BO
,
Ryan JJoan
,
Phipps J
,
Buttolph L
,
Bray B
,
Aslan JE
,
Metz TO
,
Stevens JF
,
Bradley R
. 2022.
Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.
.
Trials. 23(1):885.
Microsomes
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Middle Aged
Kuiper HC
,
Langsdorf BL
,
Miranda CL
,
Joss J
,
Jubert C
,
Mata JE
,
Stevens JF
. 2010.
Quantitation of mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites in a smoking cessation study.
.
Free Radic Biol Med. 48(1):65-72.
Mitochondria
Axton ER
,
Beaver LM
,
St Mary L
,
Truong L
,
Logan CR
,
Spagnoli S
,
Prater MC
,
Keller RM
,
Garcia-Jaramillo M
,
Ehrlicher SE
et al.
. 2019.
Treatment with Nitrate, but Not Nitrite, Lowers the Oxygen Cost of Exercise and Decreases Glycolytic Intermediates While Increasing Fatty Acid Metabolites in Exercised Zebrafish.
.
J Nutr. 149(12):2120-2132.
Mitochondria, Heart
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Mitochondrial Proteins
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Models, Biological
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
Kirkwood JS
,
Miranda CL
,
Bobe G
,
Maier CS
,
Stevens JF
. 2016.
18O-Tracer Metabolomics Reveals Protein Turnover and CDP-Choline Cycle Activity in Differentiating 3T3-L1 Pre-Adipocytes.
.
PLoS One. 11(6):e0157118.
Models, Chemical
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Kuiper HC
,
Miranda CL
,
Sowell JD
,
Stevens JF
. 2008.
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
.
J Biol Chem. 283(25):17131-8.
Molecular Docking Simulation
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Molecular Dynamics Simulation
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Molecular Probes
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Molecular Structure
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Kesinger NG
,
Stevens JF
. 2009.
Covalent interaction of ascorbic acid with natural products.
.
Phytochemistry. 70(17-18):1930-9.
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
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