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Found 460 results
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Stevens, Jan F
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Brain
Choi J
,
Leonard SW
,
Kasper K
,
McDougall M
,
Stevens JF
,
Tanguay RL
,
Traber MG
. 2015.
Novel function of vitamin E in regulation of zebrafish (Danio rerio) brain lysophospholipids discovered using lipidomics.
.
J Lipid Res. 56(6):1182-90.
Body Weight
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
Blood Glucose
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
Miranda CL
,
Elias VD
,
Hay JJ
,
Choi J
,
Reed RL
,
Stevens JF
. 2016.
Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.
.
Arch Biochem Biophys. 599:22-30.
Biotransformation
Farley SM
,
Leonard SW
,
Stevens JF
,
Traber MG
. 2014.
Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.
.
Mol Nutr Food Res. 58(8):1610-9.
Biomarkers
Kuiper HC
,
Bruno RS
,
Traber MG
,
Stevens JF
. 2011.
Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.
.
Free Radic Biol Med. 50(7):848-53.
Kuiper HC
,
Miranda CL
,
Sowell JD
,
Stevens JF
. 2008.
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
.
J Biol Chem. 283(25):17131-8.
Kuiper HC
,
Stevens JF
. 2011.
LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.
.
Curr Protoc Toxicol. Chapter 17:Unit17.14.2.
Biological Transport
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Minato Y
,
Fassio SR
,
Kirkwood JS
,
Halang P
,
Quinn MJ
,
Faulkner WJ
,
Aagesen AM
,
Steuber J
,
Stevens JF
,
Häse CC
. 2014.
Roles of the sodium-translocating NADH:quinone oxidoreductase (Na+-NQR) on vibrio cholerae metabolism, motility and osmotic stress resistance.
.
PLoS One. 9(5):e97083.
Biological Availability
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Behavior, Animal
Johnson LA
,
Zuloaga KL
,
Kugelman TL
,
Mader KS
,
Morré JT
,
Zuloaga DG
,
Weber S
,
Marzulla T
,
Mulford A
,
Button D
et al.
. 2016.
Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.
.
EBioMedicine. 3:26-42.
McDougall MQ
,
Choi J
,
Stevens JF
,
Truong L
,
Tanguay RL
,
Traber MG
. 2016.
Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos.
.
Redox Biol. 8:165-74.
Beer
Stevens JF
,
Page JE
. 2004.
Xanthohumol and related prenylflavonoids from hops and beer: to your good health!
.
Phytochemistry. 65(10):1317-30.
Ascorbic Acid Deficiency
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
Ascorbic Acid
Kesinger NG
,
Langsdorf BL
,
Yokochi AF
,
Miranda CL
,
Stevens JF
. 2010.
Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal.
.
Chem Res Toxicol. 23(4):836-44.
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Kuiper HC
,
Bruno RS
,
Traber MG
,
Stevens JF
. 2011.
Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.
.
Free Radic Biol Med. 50(7):848-53.
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
Kesinger NG
,
Stevens JF
. 2009.
Covalent interaction of ascorbic acid with natural products.
.
Phytochemistry. 70(17-18):1930-9.
Aryldialkylphosphatase
Kesinger NG
,
Langsdorf BL
,
Yokochi AF
,
Miranda CL
,
Stevens JF
. 2010.
Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal.
.
Chem Res Toxicol. 23(4):836-44.
Area Under Curve
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Apoptosis
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
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