Found 610 results
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Filters: Author is Williams, David E  [Clear All Filters]
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Liver
Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE.  2006.  Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.. Toxicol Sci. 90(1):61-72.
Williams DE.  2012.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.. Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Larsen-Su SA, Krueger SK, Yueh MFei, Pereira CB, Williams DE.  2002.  Developmental regulation of flavin-containing monooxygenase form 1 in the liver and kidney of fetal and neonatal rabbits.. Biochem Pharmacol. 63(7):1353-9.
Liver Neoplasms
Simonich MT, Egner PA, Roebuck BD, Orner GA, Jubert C, Pereira C, Groopman JD, Kensler TW, Dashwood RH, Williams DE et al..  2007.  Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.. Carcinogenesis. 28(6):1294-302.
Liver Neoplasms, Experimental
Williams DE.  2012.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.. Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE.  2006.  Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.. Toxicol Sci. 90(1):61-72.
Lung
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Henderson MC, Krueger SK, Stevens JF, Williams DE.  2004.  Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.. Chem Res Toxicol. 17(5):633-40.
Siddens LK, Henderson MC, VanDyke JE, Williams DE, Krueger SK.  2008.  Characterization of mouse flavin-containing monooxygenase transcript levels in lung and liver, and activity of expressed isoforms.. Biochem Pharmacol. 75(2):570-9.
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, Williams DE.  2015.  Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.. Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Krueger SK, Martin SR, Yueh M-F, Pereira CB, Williams DE.  2002.  Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.. Drug Metab Dispos. 30(1):34-41.
Lung Neoplasms
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Macaca mulatta
Krueger SK, Martin SR, Yueh M-F, Pereira CB, Williams DE.  2002.  Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.. Drug Metab Dispos. 30(1):34-41.
Magnesium
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Male
Wang R, W Dashwood M, Löhr CV, Fischer KA, Nakagama H, Williams DE, Dashwood RH.  2008.  beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.. Cancer Sci. 99(9):1754-9.
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Ho E, Beaver LM, Williams DE, Dashwood RH.  2011.  Dietary factors and epigenetic regulation for prostate cancer prevention.. Adv Nutr. 2(6):497-510.
Wang R, Kang Y, Löhr CV, Fischer KA, C Bradford S, Johnson G, Dashwood WMohaiza, Williams DE, Ho E, Dashwood RH.  2016.  Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.. Cancer Lett. 381(2):341-8.
Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang JH, Löhr CV, Williams DE et al..  2017.  Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.. J Nutr Biochem. 42:72-83.
Simonich MT, Egner PA, Roebuck BD, Orner GA, Jubert C, Pereira C, Groopman JD, Kensler TW, Dashwood RH, Williams DE et al..  2007.  Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.. Carcinogenesis. 28(6):1294-302.
Chen Y-S, Wang R, Dashwood W-M, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH.  2017.  A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.. Arch Toxicol. 91(10):3415-3425.
Watson GW, Wickramasekara S, Fang Y, Maier CS, Williams DE, Dashwood RH, Perez VI, Ho E.  2016.  HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.. Exp Biol Med (Maywood). 241(11):1177-85.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.

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