Found 467 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Hagen, Tory M  [Clear All Filters]
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Rats, Inbred F344
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu R-M, Hagen TM.  2004.  Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.. Proc Natl Acad Sci U S A. 101(10):3381-6.
Thomas NO, Shay KP, Kelley AR, Butler JA, Hagen TM.  2016.  Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.. Redox Biol. 10:45-52.
Gómez LA, Heath S-HD, Hagen TM.  2012.  Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.. Mech Ageing Dev. 133(2-3):99-106.
Rats, Sprague-Dawley
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Rats, Zucker
Butler JA, Hagen TM, Moreau R.  2009.  Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.. Arch Biochem Biophys. 485(1):63-71.
Reactive Nitrogen Species
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.
Reactive Oxygen Species
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.
Real-Time Polymerase Chain Reaction
Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.
Receptors, LDL
Zhang W-J, Bird KE, McMillen TS, Leboeuf RC, Hagen TM, Frei B.  2008.  Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.. Circulation. 117(3):421-8.
Reverse Transcriptase Polymerase Chain Reaction
Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.
RNA Caps
Shay KPetersen, Michels AJ, Li W, Kong A-NTony, Hagen TM.  2012.  Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.. Biochim Biophys Acta. 1823(6):1102-9.
RNA, Messenger
Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu R-M, Hagen TM.  2004.  Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid.. Proc Natl Acad Sci U S A. 101(10):3381-6.
RNA, Small Interfering
Shenvi SV, Smith EJ, Hagen TM.  2009.  Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.. Pharmacol Res. 60(4):229-36.
Sarcolemma
Monette JS, Gómez LA, Moreau RF, Bemer BA, Taylor AW, Hagen TM.  2010.  Characteristics of the rat cardiac sphingolipid pool in two mitochondrial subpopulations.. Biochem Biophys Res Commun. 398(2):272-7.
Serine
Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.
Serum Albumin
Moreau R, Heath S-HD, Doneanu CE, J Lindsay G, Hagen TM.  2003.  Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.. Antioxid Redox Signal. 5(5):517-27.
Sex Factors
Keith DJ, Butler JA, Bemer B, Dixon B, Johnson S, Garrard M, Sudakin DL, J Christensen M, Pereira C, Hagen TM.  2012.  Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.. Pharmacol Res. 66(3):199-206.
Signal Transduction
Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.
Sirolimus
Shay KPetersen, Michels AJ, Li W, Kong A-NTony, Hagen TM.  2012.  Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.. Biochim Biophys Acta. 1823(6):1102-9.
Sodium
Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.
Sodium-Coupled Vitamin C Transporters
Michels AJ, Hagen TM, Frei B.  2013.  Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.. Annu Rev Nutr. 33:45-70.
Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.
Spectrometry, Fluorescence
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.

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