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Faculty and Staff
Our Research
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Biblio
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Dashwood, Roderick H
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Humans
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Higdon JV
,
Delage B
,
Williams DE
,
Dashwood RH
. 2007.
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
.
Pharmacol Res. 55(3):224-36.
Myzak MC
,
Dashwood RH
. 2006.
Chemoprotection by sulforaphane: keep one eye beyond Keap1.
.
Cancer Lett. 233(2):208-18.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Watson GW
,
Wickramasekara S
,
Fang Y
,
Palomera-Sanchez Z
,
Maier CS
,
Williams DE
,
Dashwood RH
,
Perez VI
,
Ho E
. 2015.
Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.
.
Mol Nutr Food Res. 59(10):1954-61.
Delage B
,
Dashwood RH
. 2008.
Dietary manipulation of histone structure and function.
.
Annu Rev Nutr. 28:347-66.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Larsen CA
,
Dashwood RH
,
Bisson WH
. 2010.
Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.
.
Pharmacol Res. 62(6):457-64.
Dashwood RH
. 2002.
Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.
.
Mutat Res. 511(2):89-112.
Larsen CA
,
Dashwood RH
. 2009.
Suppression of Met activation in human colon cancer cells treated with (-)-epigallocatechin-3-gallate: minor role of hydrogen peroxide.
.
Biochem Biophys Res Commun. 389(3):527-30.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Carter O
,
Bailey GS
,
Dashwood RH
. 2004.
The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
.
J Nutr. 134(12 Suppl):3441S-3444S.
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Li Q
,
Löhr CV
,
Dashwood RH
. 2009.
Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
.
Cancer Lett. 283(1):36-42.
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Myzak MC
,
Dashwood RH
. 2006.
Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.
.
Curr Drug Targets. 7(4):443-52.
Beaver LM
,
Kuintzle R
,
Buchanan A
,
Wiley MW
,
Glasser ST
,
Wong CP
,
Johnson GS
,
Chang JH
,
Löhr CV
,
Williams DE
et al.
. 2017.
Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.
.
J Nutr Biochem. 42:72-83.
Dashwood RH
. 2006.
Xenobiotic metabolism relevance to cancer.
.
J Nutr. 136(10):2681S-2S.
Ho E
,
Beaver LM
,
Williams DE
,
Dashwood RH
. 2011.
Dietary factors and epigenetic regulation for prostate cancer prevention.
.
Adv Nutr. 2(6):497-510.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
Myzak MC
,
Ho E
,
Dashwood RH
. 2006.
Dietary agents as histone deacetylase inhibitors.
.
Mol Carcinog. 45(6):443-6.
Dashwood RH
. 2007.
Frontiers in polyphenols and cancer prevention.
.
J Nutr. 137(1 Suppl):267S-269S.
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