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Faculty and Staff
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Biblio
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Hagen, Tory M
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Animals
Suh JH
,
Heath S-H
,
Hagen TM
. 2003.
Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.
.
Free Radic Biol Med. 35(9):1064-72.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Michels AJ
,
Joisher N
,
Hagen TM
. 2003.
Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.
.
Arch Biochem Biophys. 410(1):112-20.
Rodríguez E
,
Radke A
,
Hagen TM
,
Blier PU
. 2022.
Supercomplex Organization of the Electron Transfer System in Marine Bivalves, a Model of Extreme Longevity.
.
J Gerontol A Biol Sci Med Sci. 77(2):283-290.
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
AMP-Activated Protein Kinases
Butler JA
,
Hagen TM
,
Moreau R
. 2009.
Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.
.
Arch Biochem Biophys. 485(1):63-71.
Amino Acid Sequence
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
Harris RA
,
Hagen TM
. 2004.
Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.
.
Biochem Biophys Res Commun. 325(1):48-58.
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Aldehydes
Suh JH
,
Heath S-H
,
Hagen TM
. 2003.
Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.
.
Free Radic Biol Med. 35(9):1064-72.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Aging
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Suh JH
,
Heath S-H
,
Hagen TM
. 2003.
Two subpopulations of mitochondria in the aging rat heart display heterogenous levels of oxidative stress.
.
Free Radic Biol Med. 35(9):1064-72.
Michels AJ
,
Joisher N
,
Hagen TM
. 2003.
Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.
.
Arch Biochem Biophys. 410(1):112-20.
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Li L
,
Smith A
,
Hagen TM
,
Frei B
. 2010.
Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.
.
Ann N Y Acad Sci. 1203:151-9.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Suh JH
,
Moreau R
,
Heath S-HD
,
Hagen TM
. 2005.
Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.
.
Redox Rep. 10(1):52-60.
Smith EJ
,
Shay KP
,
Thomas NO
,
Butler JA
,
Finlay LF
,
Hagen TM
. 2015.
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
.
Free Radic Biol Med. 89:1184-91.
Gómez LA
,
Hagen TM
. 2012.
Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?
Semin Cell Dev Biol. 23(7):758-67.
Thomas NO
,
Shay KP
,
Kelley AR
,
Butler JA
,
Hagen TM
. 2016.
Glutathione maintenance mitigates age-related susceptibility to redox cycling agents.
.
Redox Biol. 10:45-52.
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