Found 1386 results
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Transcriptome
Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH, Zhang Y, Becker KG et al..  2014.  Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.. PLoS One. 9(1):e83988.
Transcriptional Activation
Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.
Transcription, Genetic
Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.
Kang Y, Nian H, Rajendran P, Kim E, Dashwood WM, Pinto JT, Boardman LA, Thibodeau SN, Limburg PJ, Löhr CV et al..  2014.  HDAC8 and STAT3 repress BMF gene activity in colon cancer cells.. Cell Death Dis. 5:e1476.
Abbas A, J Hall A, Patterson WL, Ho E, Hsu A, Al-Mulla F, Georgel PT.  2016.  Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.. Biochem Cell Biol. 94(1):71-81.
Trans-Activators
Blum CA, Tanaka T, Zhong X, Li Q, Dashwood W-M, Pereira C, Xu M, Dashwood RH.  2003.  Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.. Mol Carcinog. 36(4):195-203.
Toxicokinetics
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Tilton SC, Vertel EA, Anderson KA, Tidwell LG, Ognibene TJ, Turteltaub KW et al..  2023.  Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.. Toxicol Appl Pharmacol. 460:116377.
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Labut EM, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ et al..  2023.  Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.. Chem Biol Interact. 382:110608.
Toxicogenetics
Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE.  2006.  Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.. Toxicol Sci. 90(1):61-72.
TOR Serine-Threonine Kinases
Wang R, Yu Z, Sunchu B, Shoaf J, Dang I, Zhao S, Caples K, Bradley L, Beaver LM, Ho E et al..  2017.  Rapamycin inhibits the secretory phenotype of senescent cells by a Nrf2-independent mechanism.. Aging Cell. 16(3):564-574.
Wang R, Sunchu B, Perez VI.  2017.  Rapamycin and the inhibition of the secretory phenotype.. Exp Gerontol. 94:89-92.
Tolbutamide
Liu J, Banuvar S, Viana M, Barengolts E, Chen S-N, Pauli GF, van Breemen RB.  2023.  Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants.. Drug Metab Dispos. 51(2):199-204.
Tobacco Use Cessation Devices
Mah E, Pei R, Guo Y, Masterjohn C, Ballard KD, Taylor BA, Taylor AW, Traber MG, Volek JS, Bruno RS.  2015.  Greater γ-tocopherol status during acute smoking abstinence with nicotine replacement therapy improved vascular endothelial function by decreasing 8-iso-15(S)-prostaglandin F2α.. Exp Biol Med (Maywood). 240(4):527-33.
Tissue Distribution
Jubert C, Mata J, Bench G, Dashwood R, Pereira C, Tracewell W, Turteltaub K, Williams D, Bailey G.  2009.  Effects of chlorophyll and chlorophyllin on low-dose aflatoxin B(1) pharmacokinetics in human volunteers.. Cancer Prev Res (Phila). 2(12):1015-22.
Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS.  2008.  Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.. Food Chem Toxicol. 46(3):1014-24.
Time Factors
Reitsma SE, Lakshmanan HHara Sudha, Johnson J, Pang J, Parra-Izquierdo I, Melrose AR, Choi J, Anderson DEJ, Hinds MT, Stevens JFrederik et al..  2022.  Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.. Am J Physiol Cell Physiol. 322(3):C370-C381.
Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.
Reitsma SE, Lakshmanan HHara Sudha, Johnson J, Pang J, Parra-Izquierdo I, Melrose AR, Choi J, Anderson DEJ, Hinds MT, Stevens JFrederik et al..  2022.  Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.. Am J Physiol Cell Physiol. 322(3):C370-C381.
Hall JA, Bobe G, Nixon BK, Vorachek WR, Nichols T, Mosher WD, Pirelli GJ.  2014.  Effect of transport on blood selenium and glutathione status in feeder lambs.. J Anim Sci. 92(9):4115-22.
Tibia
Martin SA, Riordan RT, Wang R, Yu Z, Aguirre-Burk AM, Wong CP, Olson DA, Branscum AJ, Turner RT, Iwaniec UT et al..  2021.  Rapamycin impairs bone accrual in young adult mice independent of Nrf2.. Exp Gerontol. 154:111516.
Thromboxanes
Reitsma SE, Lakshmanan HHara Sudha, Johnson J, Pang J, Parra-Izquierdo I, Melrose AR, Choi J, Anderson DEJ, Hinds MT, Stevens JFrederik et al..  2022.  Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.. Am J Physiol Cell Physiol. 322(3):C370-C381.
Reitsma SE, Lakshmanan HHara Sudha, Johnson J, Pang J, Parra-Izquierdo I, Melrose AR, Choi J, Anderson DEJ, Hinds MT, Stevens JFrederik et al..  2022.  Chronic edible dosing of Δ9-tetrahydrocannabinol (THC) in nonhuman primates reduces systemic platelet activity and function.. Am J Physiol Cell Physiol. 322(3):C370-C381.
Thiosemicarbazones
Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Paul B, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI et al..  2024.  Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.. Sci Rep. 14(1):5929.
Thioctic Acid
Finlay LA, Michels AJ, Butler JA, Smith EJ, Monette JS, Moreau RF, Petersen SKate, Frei B, Hagen TM.  2012.  R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.. Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Keith DJ, Butler JA, Bemer B, Dixon B, Johnson S, Garrard M, Sudakin DL, J Christensen M, Pereira C, Hagen TM.  2012.  Age and gender dependent bioavailability of R- and R,S-α-lipoic acid: a pilot study.. Pharmacol Res. 66(3):199-206.

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