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Leonard, Scott W
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Self Administration
Lebold KM
,
Grant KA
,
Freeman WM
,
Wiren KM
,
Miller GW
,
Kiley C
,
Leonard SW
,
Traber MG
. 2011.
Individual differences in hyperlipidemia and vitamin E status in response to chronic alcohol self-administration in cynomolgus monkeys.
.
Alcohol Clin Exp Res. 35(3):474-83.
Research Design
Traber MG
,
Leonard SW
,
Ebenuwa I
,
Violet P-C
,
Wang Y
,
Niyyati M
,
Padayatty S
,
Tu H
,
Courville A
,
Bernstein S
et al.
. 2019.
Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.
.
Am J Clin Nutr. 110(5):1148-1167.
Reproducibility of Results
Leonard SW
,
Bruno RS
,
Paterson E
,
Schock BC
,
Atkinson J
,
Bray TM
,
Cross CE
,
Traber MG
. 2003.
5-nitro-gamma-tocopherol increases in human plasma exposed to cigarette smoke in vitro and in vivo.
.
Free Radic Biol Med. 35(12):1560-7.
Leonard SW
,
Gumpricht E
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2005.
Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration.
.
J Lipid Res. 46(5):1068-75.
Regression Analysis
Traber MG
,
Leonard SW
,
Traber DL
,
Traber LD
,
Gallagher J
,
Bobe G
,
Jeschke MG
,
Finnerty CC
,
Herndon D
. 2010.
α-Tocopherol adipose tissue stores are depleted after burn injury in pediatric patients.
.
Am J Clin Nutr. 92(6):1378-84.
Reference Values
Traber MG
,
Leonard SW
,
Traber DL
,
Traber LD
,
Gallagher J
,
Bobe G
,
Jeschke MG
,
Finnerty CC
,
Herndon D
. 2010.
α-Tocopherol adipose tissue stores are depleted after burn injury in pediatric patients.
.
Am J Clin Nutr. 92(6):1378-84.
Receptors, Aryl Hydrocarbon
Traber MG
,
Mustacich DJ
,
Sullivan LC
,
Leonard SW
,
Ahern-Rindell A
,
Kerkvliet N
. 2010.
Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.
.
J Nutr Biochem. 21(12):1193-9.
Reactive Nitrogen Species
Pei R
,
Mah E
,
Leonard SW
,
Traber MG
,
Bruno RS
. 2015.
α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers.
.
Free Radic Res. 49(9):1114-1121.
Rats, Sprague-Dawley
Mustacich DJ
,
Vo AT
,
Elias VD
,
Payne K
,
Sullivan L
,
Leonard SW
,
Traber MG
. 2007.
Regulatory mechanisms to control tissue alpha-tocopherol.
.
Free Radic Biol Med. 43(4):610-8.
Leonard SW
,
Gumpricht E
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2005.
Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration.
.
J Lipid Res. 46(5):1068-75.
Traber MG
,
Labut EM
,
Leonard SW
,
Lebold KM
. 2011.
α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes.
.
Free Radic Biol Med. 51(11):2031-40.
Farley SM
,
Leonard SW
,
Stevens JF
,
Traber MG
. 2014.
Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.
.
Mol Nutr Food Res. 58(8):1610-9.
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Mustacich DJ
,
Leonard SW
,
Patel NK
,
Traber MG
. 2010.
Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.
.
Free Radic Biol Med. 48(1):73-81.
Mustacich DJ
,
Leonard SW
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2006.
Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.
.
Free Radic Biol Med. 41(7):1069-78.
Tennant KG
,
Leonard SW
,
Wong CP
,
Iwaniec UT
,
Turner RT
,
Traber MG
. 2017.
High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation.
.
J Med Food. 20(7):700-708.
Rats
Tennant KG
,
Leonard SW
,
Wong CP
,
Iwaniec UT
,
Turner RT
,
Traber MG
. 2017.
High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation.
.
J Med Food. 20(7):700-708.
Mustacich DJ
,
Vo AT
,
Elias VD
,
Payne K
,
Sullivan L
,
Leonard SW
,
Traber MG
. 2007.
Regulatory mechanisms to control tissue alpha-tocopherol.
.
Free Radic Biol Med. 43(4):610-8.
Leonard SW
,
Gumpricht E
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2005.
Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration.
.
J Lipid Res. 46(5):1068-75.
Traber MG
,
Labut EM
,
Leonard SW
,
Lebold KM
. 2011.
α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes.
.
Free Radic Biol Med. 51(11):2031-40.
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Mustacich DJ
,
Leonard SW
,
Patel NK
,
Traber MG
. 2010.
Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.
.
Free Radic Biol Med. 48(1):73-81.
Mustacich DJ
,
Leonard SW
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2006.
Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.
.
Free Radic Biol Med. 41(7):1069-78.
Propionates
Leonard SW
,
Traber MG
. 2006.
Measurement of the vitamin E metabolites, carboxyethyl hydroxychromans (CEHCs), in biological samples.
.
Curr Protoc Toxicol. Chapter 7:Unit7.8.
Traber MG
,
Siddens LK
,
Leonard SW
,
Schock B
,
Gohil K
,
Krueger SK
,
Cross CE
,
Williams DE
. 2005.
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
.
Free Radic Biol Med. 38(6):773-85.
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