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Faculty and Staff
Our Research
Micronutrient Information
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Cataract
Carr AC
,
Frei B
. 1999.
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans.
.
Am J Clin Nutr. 69(6):1086-107.
Cell Adhesion
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
Cell Adhesion Molecules
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Cell Line
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Cells, Cultured
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
Suh JH
,
Shigeno ET
,
Morrow JD
,
Cox B
,
Rocha AE
,
Frei B
,
Hagen TM
. 2001.
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.
.
FASEB J. 15(3):700-6.
Ceramides
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2008.
Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.
.
Br J Pharmacol. 153(8):1615-22.
Chalcone
Miranda CL
,
Stevens JF
,
Ivanov V
,
McCall M
,
Frei B
,
Deinzer ML
,
Buhler DR
. 2000.
Antioxidant and prooxidant actions of prenylated and nonprenylated chalcones and flavanones in vitro.
.
J Agric Food Chem. 48(9):3876-84.
Chemokine CCL2
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Frei B
. 1999.
On the role of vitamin C and other antioxidants in atherogenesis and vascular dysfunction.
.
Proc Soc Exp Biol Med. 222(3):196-204.
Chloramines
McCall MR
,
Carr AC
,
Forte TM
,
Frei B
. 2001.
Ldl modified by hypochlorous acid is a potent inhibitor of lecithin-cholesterol acyltransferase activity.
.
Arterioscler Thromb Vasc Biol. 21(6):1040-5.
Carr AC
,
Tijerina T
,
Frei B
. 2000.
Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein.
.
Biochem J. 346 Pt 2:491-9.
Carr AC
,
Hawkins CL
,
Thomas SR
,
Stocker R
,
Frei B
. 2001.
Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents.
.
Free Radic Biol Med. 30(5):526-36.
Carr AC
,
Hawkins CL
,
Thomas SR
,
Stocker R
,
Frei B
. 2001.
Relative reactivities of N-chloramines and hypochlorous acid with human plasma constituents.
.
Free Radic Biol Med. 30(5):526-36.
Chlorides
Carr AC
,
Frei B
. 2001.
The nitric oxide congener nitrite inhibits myeloperoxidase/H2O2/ Cl- -mediated modification of low density lipoprotein.
.
J Biol Chem. 276(3):1822-8.
Chromatography, Gel
Ivanov V
,
Carr AC
,
Frei B
. 2001.
Red wine antioxidants bind to human lipoproteins and protect them from metal ion-dependent and -independent oxidation.
.
J Agric Food Chem. 49(9):4442-9.
Clinical Trials as Topic
Carr AC
,
Frei B
. 1999.
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans.
.
Am J Clin Nutr. 69(6):1086-107.
Copper
Ivanov V
,
Carr AC
,
Frei B
. 2001.
Red wine antioxidants bind to human lipoproteins and protect them from metal ion-dependent and -independent oxidation.
.
J Agric Food Chem. 49(9):4442-9.
Coronary Disease
Carr A
,
Frei B
. 2000.
The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide.
.
Free Radic Biol Med. 28(12):1806-14.
Cysteine
McCall MR
,
Carr AC
,
Forte TM
,
Frei B
. 2001.
Ldl modified by hypochlorous acid is a potent inhibitor of lecithin-cholesterol acyltransferase activity.
.
Arterioscler Thromb Vasc Biol. 21(6):1040-5.
Dietary Supplements
Suh JH
,
Shigeno ET
,
Morrow JD
,
Cox B
,
Rocha AE
,
Frei B
,
Hagen TM
. 2001.
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.
.
FASEB J. 15(3):700-6.
Carr A
,
Frei B
. 1999.
Does vitamin C act as a pro-oxidant under physiological conditions?
FASEB J. 13(9):1007-24.
Disease Models, Animal
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
DNA Damage
Suh JH
,
Shigeno ET
,
Morrow JD
,
Cox B
,
Rocha AE
,
Frei B
,
Hagen TM
. 2001.
Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.
.
FASEB J. 15(3):700-6.
McCall MR
,
Frei B
. 1999.
Can antioxidant vitamins materially reduce oxidative damage in humans?
Free Radic Biol Med. 26(7-8):1034-53.
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