Linus Pauling Institute

Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.  2001.  Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.. FASEB J. 15(3):700-6.

Taylor AW, Bruno RS, Traber MG.  2008.  Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology.. Lipids. 43(10):925-36.

Forman HJay, Traber M, Ursini F.  2014.  Antioxidants: GRABbing new headlines.. Free Radic Biol Med. 66:1-2.

Bruno RS, Traber MG.  2005.  Cigarette smoke alters human vitamin E requirements.. J Nutr. 135(4):671-4.

Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.

Frei B, Birlouez-Aragon I, Lykkesfeldt J.  2012.  Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr. 52(9):815-29.

Li L, Frei B.  2006.  Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.. Arterioscler Thromb Vasc Biol. 26(12):2638-43.

Li L, Smith A, Hagen TM, Frei B.  2010.  Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.. Ann N Y Acad Sci. 1203:151-9.

Kuiper HC, Stevens JF.  2011.  LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.. Curr Protoc Toxicol. Chapter 17:Unit17.14.2.

Kirkwood JS, Legette LCL, Miranda CL, Jiang Y, Stevens JF.  2013.  A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.. J Biol Chem. 288(26):19000-13.

Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.  2002.  Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.. Proc Natl Acad Sci U S A. 99(4):1870-5.

McDougall M, Choi J, Truong L, Tanguay R, Traber MG.  2017.  Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.. Free Radic Biol Med. 110:250-260.

Li C, Zhang W-J, Choi J, Frei B.  2016.  Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.. Redox Biol. 9:220-228.

Visioli F, Ingram A, Beckman JS, Magnusson KR, Hagen TM.  2022.  Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help? Free Radic Biol Med. 178:330-346.

Higdon JV, Frei B.  2003.  Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.. Crit Rev Food Sci Nutr. 43(1):89-143.

Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.

Bruno RS, Leonard SW, Li J, Bray TM, Traber MG.  2005.  Lower plasma alpha-carboxyethyl-hydroxychroman after deuterium-labeled alpha-tocopherol supplementation suggests decreased vitamin E metabolism in smokers.. Am J Clin Nutr. 81(5):1052-9.

Lytle KA, Jump DB.  2016.  Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible? PLoS One. 11(1):e0146942.

Smith AR, Visioli F, Hagen TM.  2002.  Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.. FASEB J. 16(9):1102-4.

Depner CM, Torres-Gonzalez M, Tripathy S, Milne G, Jump DB.  2012.  Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.. J Nutr. 142(8):1495-503.

Bella DL, Schock BC, Lim Y, Leonard SW, Berry C, Cross CE, Traber MG.  2006.  Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stress.. Lipids. 41(2):105-12.

Mastaloudis A, Leonard SW, Traber MG.  2001.  Oxidative stress in athletes during extreme endurance exercise.. Free Radic Biol Med. 31(7):911-22.

Kuiper HC, Bruno RS, Traber MG, Stevens JF.  2011.  Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.. Free Radic Biol Med. 50(7):848-53.

Li L, Frei B.  2009.  Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.. Arterioscler Thromb Vasc Biol. 29(5):732-8.

Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.