Found 610 results
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Filters: Author is Williams, David E  [Clear All Filters]
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Carcinogens
Parasramka MA, W Dashwood M, Wang R, Abdelli A, Bailey GS, Williams DE, Ho E, Dashwood RH.  2012.  MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.. Mol Nutr Food Res. 56(8):1259-69.
Wang R, W Dashwood M, Löhr CV, Fischer KA, Nakagama H, Williams DE, Dashwood RH.  2008.  beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.. Cancer Sci. 99(9):1754-9.
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.
Carcinogenicity Tests
Chen Y-S, Wang R, Dashwood W-M, Löhr CV, Williams DE, Ho E, Mertens-Talcott S, Dashwood RH.  2017.  A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.. Arch Toxicol. 91(10):3415-3425.
Carcinogenesis
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Carbon Radioisotopes
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.
Caprylates
Williams DE.  2012.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.. Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Calcium Signaling
Leibelt DA, Hedstrom OR, Fischer KA, Pereira CB, Williams DE.  2003.  Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3'-diindolylmethane in sprague-dawley rats.. Toxicol Sci. 74(1):10-21.
Calcium
Leibelt DA, Hedstrom OR, Fischer KA, Pereira CB, Williams DE.  2003.  Evaluation of chronic dietary exposure to indole-3-carbinol and absorption-enhanced 3,3'-diindolylmethane in sprague-dawley rats.. Toxicol Sci. 74(1):10-21.
Caffeine
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Caco-2 Cells
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Brassicaceae
Higdon JV, Delage B, Williams DE, Dashwood RH.  2007.  Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.. Pharmacol Res. 55(3):224-36.
Brassica
Bouranis JA, Beaver LM, Jiang D, Choi J, Wong CP, Davis EW, Williams DE, Sharpton TJ, Stevens JF, Ho E.  2022.  Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.. Nutrients. 15(1)
Brain
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Blotting, Western
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Krueger SK, Martin SR, Yueh M-F, Pereira CB, Williams DE.  2002.  Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.. Drug Metab Dispos. 30(1):34-41.
Biotransformation
Krueger SK, VanDyke JE, Williams DE, Hines RN.  2006.  The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines.. Drug Metab Rev. 38(1-2):139-47.
Biomarkers, Tumor
Bailey GS, Reddy AP, Pereira CB, Harttig U, Baird W, Spitsbergen JM, Hendricks JD, Orner GA, Williams DE, Swenberg JA.  2009.  Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.. Chem Res Toxicol. 22(7):1264-76.
beta-Naphthoflavone
Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE.  2006.  Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.. Toxicol Sci. 90(1):61-72.
beta Catenin
Wang R, W Dashwood M, Löhr CV, Fischer KA, Nakagama H, Williams DE, Dashwood RH.  2008.  beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.. Cancer Sci. 99(9):1754-9.
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.
Benzopyrenes
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, Williams DE.  2015.  Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.. Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Williams DE.  2012.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.. Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.

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