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Oxidants
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
Frei B
,
Lawson S
. 2008.
Vitamin C and cancer revisited.
.
Proc Natl Acad Sci U S A. 105(32):11037-8.
Oxidation-Reduction
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Lotito SB
,
Frei B
. 2004.
Relevance of apple polyphenols as antioxidants in human plasma: contrasting in vitro and in vivo effects.
.
Free Radic Biol Med. 36(2):201-11.
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
Oxidative Stress
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Zhu B-Z
,
Carr AC
,
Frei B
. 2002.
Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.
.
FEBS Lett. 532(1-2):80-4.
Li L
,
Smith A
,
Hagen TM
,
Frei B
. 2010.
Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.
.
Ann N Y Acad Sci. 1203:151-9.
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Frei B
,
Birlouez-Aragon I
,
Lykkesfeldt J
. 2012.
Authors' perspective: What is the optimum intake of vitamin C in humans?
Crit Rev Food Sci Nutr. 52(9):815-29.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Oxidoreductases
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
Oxygen
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
p38 Mitogen-Activated Protein Kinases
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Parkinson Disease
Higdon JV
,
Frei B
. 2006.
Coffee and health: a review of recent human research.
.
Crit Rev Food Sci Nutr. 46(2):101-23.
Period Circadian Proteins
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Peroxidase
Zhang W-J
,
Frei B
. 2015.
Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.
.
Mediators Inflamm. 2015:274314.
Phagocytes
Zhang W-J
,
Wei H
,
Tien Y-T
,
Frei B
. 2011.
Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.
.
Free Radic Biol Med. 50(11):1517-25.
Phenanthrolines
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
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