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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Camellia sinensis
Yilmazer-Musa M
,
Griffith AM
,
Michels AJ
,
Schneider E
,
Frei B
. 2012.
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.
.
J Agric Food Chem. 60(36):8924-9.
Calibration
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Caffeine
Higdon JV
,
Frei B
. 2006.
Coffee and health: a review of recent human research.
.
Crit Rev Food Sci Nutr. 46(2):101-23.
Bread
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Body Weight
Zhang W-J
,
Bird KE
,
McMillen TS
,
Leboeuf RC
,
Hagen TM
,
Frei B
. 2008.
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
.
Circulation. 117(3):421-8.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Blotting, Northern
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Zhang WJian
,
Stocker R
,
McCall MR
,
Forte TM
,
Frei B
. 2002.
Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells.
.
Atherosclerosis. 165(2):241-9.
Biomarkers
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Biological Transport
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
Biological Availability
Higdon JV
,
Frei B
. 2003.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
.
Crit Rev Food Sci Nutr. 43(1):89-143.
Lotito SB
,
Frei B
. 2006.
Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?
Free Radic Biol Med. 41(12):1727-46.
Atherosclerosis
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Zhang W-J
,
Bird KE
,
McMillen TS
,
Leboeuf RC
,
Hagen TM
,
Frei B
. 2008.
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
.
Circulation. 117(3):421-8.
Li L
,
Frei B
. 2006.
Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.
.
Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Astragalus propinquus
Zhang W-J
,
Frei B
. 2015.
Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.
.
Mediators Inflamm. 2015:274314.
Ascorbic Acid Deficiency
Frei B
,
Birlouez-Aragon I
,
Lykkesfeldt J
. 2012.
Authors' perspective: What is the optimum intake of vitamin C in humans?
Crit Rev Food Sci Nutr. 52(9):815-29.
Michels AJ
,
Frei B
. 2013.
Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.
.
Nutrients. 5(12):5161-92.
Ascorbic Acid
Michels AJ
,
Hagen TM
,
Frei B
. 2013.
Human genetic variation influences vitamin C homeostasis by altering vitamin C transport and antioxidant enzyme function.
.
Annu Rev Nutr. 33:45-70.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Michels AJ
,
Frei B
. 2013.
Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.
.
Nutrients. 5(12):5161-92.
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