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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Ascorbic Acid
Frei B
,
Lawson S
. 2008.
Vitamin C and cancer revisited.
.
Proc Natl Acad Sci U S A. 105(32):11037-8.
Taylor AW
,
Bruno RS
,
Frei B
,
Traber MG
. 2006.
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.
.
Anal Biochem. 350(1):41-51.
Frei B
,
Birlouez-Aragon I
,
Lykkesfeldt J
. 2012.
Authors' perspective: What is the optimum intake of vitamin C in humans?
Crit Rev Food Sci Nutr. 52(9):815-29.
Carr AC
,
Frei B
. 2002.
Human neutrophils oxidize low-density lipoprotein by a hypochlorous acid-dependent mechanism: the role of vitamin C.
.
Biol Chem. 383(3-4):627-36.
Lotito SB
,
Frei B
. 2004.
The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.
.
Free Radic Biol Med. 37(2):251-8.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Kerr DCR
,
Zava DT
,
Piper WT
,
Saturn SR
,
Frei B
,
Gombart AF
. 2015.
Associations between vitamin D levels and depressive symptoms in healthy young adult women.
.
Psychiatry Res. 227(1):46-51.
Zhu B-Z
,
Antholine WE
,
Frei B
. 2002.
Thiourea protects against copper-induced oxidative damage by formation of a redox-inactive thiourea-copper complex.
.
Free Radic Biol Med. 32(12):1333-8.
Arteriosclerosis
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
ARNTL Transcription Factors
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Arachidonic Acid
Taylor AW
,
Bruno RS
,
Frei B
,
Traber MG
. 2006.
Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.
.
Anal Biochem. 350(1):41-51.
Apolipoproteins E
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Zhang W-J
,
Bird KE
,
McMillen TS
,
Leboeuf RC
,
Hagen TM
,
Frei B
. 2008.
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
.
Circulation. 117(3):421-8.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Aortic Diseases
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Aorta, Thoracic
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Aorta
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Li L
,
Smith A
,
Hagen TM
,
Frei B
. 2010.
Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.
.
Ann N Y Acad Sci. 1203:151-9.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Antioxidants
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
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