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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
Found 909 results
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Dashwood, Roderick H
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Colon
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Yu T-W
,
Xu M
,
Dashwood RH
. 2004.
Antimutagenic activity of spearmint.
.
Environ Mol Mutagen. 44(5):387-93.
Codon
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
Cloning, Molecular
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Chrysenes
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Chromatin Immunoprecipitation
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Chromatin Assembly and Disassembly
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Chromatin
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
Chlorophyllides
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
.
Cancer Res. 63(6):1254-61.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Carter O
,
Bailey GS
,
Dashwood RH
. 2004.
The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
.
J Nutr. 134(12 Suppl):3441S-3444S.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Chlorophyll
Simonich MT
,
Egner PA
,
Roebuck BD
,
Orner GA
,
Jubert C
,
Pereira C
,
Groopman JD
,
Kensler TW
,
Dashwood RH
,
Williams DE
et al.
. 2007.
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
.
Carcinogenesis. 28(6):1294-302.
McQuistan TJ
,
Simonich MT
,
M Pratt M
,
Pereira CB
,
Hendricks JD
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2012.
Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.
.
Food Chem Toxicol. 50(2):341-52.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Simonich MT
,
McQuistan T
,
Jubert C
,
Pereira C
,
Hendricks JD
,
Schimerlik M
,
Zhu B
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2008.
Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.
.
Food Chem Toxicol. 46(3):1014-24.
Chemoprevention
Dashwood RH
. 2003.
Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.
.
J Biochem Mol Biol. 36(1):35-42.
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Cells, Cultured
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Cell Transformation, Neoplastic
Myzak MC
,
W Dashwood M
,
Orner GA
,
Ho E
,
Dashwood RH
. 2006.
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.
.
FASEB J. 20(3):506-8.
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