Found 909 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Dashwood, Roderick H  [Clear All Filters]
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Plants, Edible
Nian H, Delage B, Ho E, Dashwood RH.  2009.  Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.. Environ Mol Mutagen. 50(3):213-21.
Poly (ADP-Ribose) Polymerase-1
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Polymerase Chain Reaction
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Polymorphism, Genetic
Higdon JV, Delage B, Williams DE, Dashwood RH.  2007.  Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.. Pharmacol Res. 55(3):224-36.
Polymorphism, Single Nucleotide
Blum CA, Tanaka T, Zhong X, Li Q, Dashwood W-M, Pereira C, Xu M, Dashwood RH.  2003.  Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.. Mol Carcinog. 36(4):195-203.
Polymorphism, Single-Stranded Conformational
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Li Q, Dixon BM, Al-Fageeh M, Blum CA, Dashwood RH.  2002.  Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.. Gene. 283(1-2):255-62.
Polyphenols
Larsen CA, Bisson WH, Dashwood RH.  2009.  Tea catechins inhibit hepatocyte growth factor receptor (MET kinase) activity in human colon cancer cells: kinetic and molecular docking studies.. J Med Chem. 52(21):6543-5.
Dashwood RH.  2007.  Frontiers in polyphenols and cancer prevention.. J Nutr. 137(1 Suppl):267S-269S.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Polyps
Orner GA, Dashwood W-M, Blum CA, G Díaz D, Li Q, Al-Fageeh M, Tebbutt N, Heath JK, Ernst M, Dashwood RH.  2002.  Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).. Mutat Res. 506-507:121-7.
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Pregnancy
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Delage B, Dashwood RH.  2008.  Dietary manipulation of histone structure and function.. Annu Rev Nutr. 28:347-66.
Pregnancy Complications, Neoplastic
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Prenatal Exposure Delayed Effects
Delage B, Dashwood RH.  2008.  Dietary manipulation of histone structure and function.. Annu Rev Nutr. 28:347-66.
Prenatal Nutritional Physiological Phenomena
Delage B, Dashwood RH.  2008.  Dietary manipulation of histone structure and function.. Annu Rev Nutr. 28:347-66.
Prodrugs
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Promoter Regions, Genetic
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, E Houseman A, Williams DE, Dashwood RH, Ho E.  2014.  Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.. PLoS One. 9(1):e86787.
Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.
Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH.  2004.  Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.. Genomics. 83(2):231-42.
Prostate
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, E Houseman A, Williams DE, Dashwood RH, Ho E.  2014.  Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.. PLoS One. 9(1):e86787.
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.
Prostatic Hyperplasia
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.
Prostatic Neoplasms
Watson GW, Wickramasekara S, Fang Y, Palomera-Sanchez Z, Maier CS, Williams DE, Dashwood RH, Perez VI, Ho E.  2015.  Analysis of autophagic flux in response to sulforaphane in metastatic prostate cancer cells.. Mol Nutr Food Res. 59(10):1954-61.

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