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Faculty and Staff
Our Research
Micronutrient Information
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Stevens, Jan F
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Rats, Sprague-Dawley
Choi J
,
Yin T
,
Shinozaki K
,
Lampe JW
,
Stevens JF
,
Becker LB
,
Kim J
. 2018.
Comprehensive analysis of phospholipids in the brain, heart, kidney, and liver: brain phospholipids are least enriched with polyunsaturated fatty acids.
.
Mol Cell Biochem. 442(1-2):187-201.
Farley SM
,
Leonard SW
,
Stevens JF
,
Traber MG
. 2014.
Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.
.
Mol Nutr Food Res. 58(8):1610-9.
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Rats, Inbred F344
Kuiper HC
,
Miranda CL
,
Sowell JD
,
Stevens JF
. 2008.
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
.
J Biol Chem. 283(25):17131-8.
Rats
Kuiper HC
,
Miranda CL
,
Sowell JD
,
Stevens JF
. 2008.
Mercapturic acid conjugates of 4-hydroxy-2-nonenal and 4-oxo-2-nonenal metabolites are in vivo markers of oxidative stress.
.
J Biol Chem. 283(25):17131-8.
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
Kirkwood JS
,
Maier C
,
Stevens JF
. 2013.
Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry.
.
Curr Protoc Toxicol. Chapter 4:Unit4.39.
Choi J
,
Yin T
,
Shinozaki K
,
Lampe JW
,
Stevens JF
,
Becker LB
,
Kim J
. 2018.
Comprehensive analysis of phospholipids in the brain, heart, kidney, and liver: brain phospholipids are least enriched with polyunsaturated fatty acids.
.
Mol Cell Biochem. 442(1-2):187-201.
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Han B
,
Stevens JF
,
Maier CS
. 2007.
Design, synthesis, and application of a hydrazide-functionalized isotope-coded affinity tag for the quantification of oxylipid-protein conjugates.
.
Anal Chem. 79(9):3342-54.
Randomized Controlled Trials as Topic
Langley BO
,
Ryan JJoan
,
Phipps J
,
Buttolph L
,
Bray B
,
Aslan JE
,
Metz TO
,
Stevens JF
,
Bradley R
. 2022.
Xanthohumol microbiome and signature in adults with Crohn's disease (the XMaS trial): a protocol for a phase II triple-masked, placebo-controlled clinical trial.
.
Trials. 23(1):885.
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Quinone Reductases
Minato Y
,
Fassio SR
,
Kirkwood JS
,
Halang P
,
Quinn MJ
,
Faulkner WJ
,
Aagesen AM
,
Steuber J
,
Stevens JF
,
Häse CC
. 2014.
Roles of the sodium-translocating NADH:quinone oxidoreductase (Na+-NQR) on vibrio cholerae metabolism, motility and osmotic stress resistance.
.
PLoS One. 9(5):e97083.
Quinic Acid
Gray NE
,
Morré J
,
Kelley J
,
Maier CS
,
Stevens JF
,
Quinn JF
,
Soumyanath A
. 2014.
Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.
.
J Alzheimers Dis. 40(2):359-73.
Magana AAlcazar
,
Vaswani A
,
Brown KS
,
Jiang Y
,
Alam MNure
,
Caruso M
,
Lak P
,
Cheong P
,
Gray NE
,
Quinn JF
et al.
. 2024.
Integrating High-Resolution Mass Spectral Data, Bioassays and Computational Models to Annotate Bioactives in Botanical Extracts: Case Study Analysis of Extract Associates Dicaffeoylquinic Acids with Protection against Amyloid-β Toxicity.
.
Molecules. 29(4)
Purine Nucleotides
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
Protein Structure, Tertiary
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Protein Hydrolysates
Wattanasiritham L
,
Theerakulkait C
,
Wickramasekara S
,
Maier CS
,
Stevens JF
. 2016.
Isolation and identification of antioxidant peptides from enzymatically hydrolyzed rice bran protein.
.
Food Chem. 192:156-62.
Protein Conformation
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Protein Carbonylation
Miranda CL
,
Reed RL
,
Kuiper HC
,
Alber S
,
Stevens JF
. 2009.
Ascorbic acid promotes detoxification and elimination of 4-hydroxy-2(E)-nonenal in human monocytic THP-1 cells.
.
Chem Res Toxicol. 22(5):863-74.
Proprotein Convertase 9
Miranda CL
,
Elias VD
,
Hay JJ
,
Choi J
,
Reed RL
,
Stevens JF
. 2016.
Xanthohumol improves dysfunctional glucose and lipid metabolism in diet-induced obese C57BL/6J mice.
.
Arch Biochem Biophys. 599:22-30.
Propiophenones
Kirkwood JS
,
Maier C
,
Stevens JF
. 2013.
Simultaneous, untargeted metabolic profiling of polar and nonpolar metabolites by LC-Q-TOF mass spectrometry.
.
Curr Protoc Toxicol. Chapter 4:Unit4.39.
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
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