Found 610 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Williams, David E  [Clear All Filters]
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
Base Sequence
Krueger SK, Williams DE, Yueh M-F, Martin SR, Hines RN, Raucy JL, Dolphin CT, Shephard EA, Phillips IR.  2002.  Genetic polymorphisms of flavin-containing monooxygenase (FMO).. Drug Metab Rev. 34(3):523-32.
Benzhydryl Compounds
Williams DE.  2018.  Association Is Not Causation.. Toxicol Sci. 164(1):3.
Benzo(a)pyrene
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Labut EM, Vertel EA, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ et al..  2023.  Impact of phenanthrene co-administration on the toxicokinetics of benzo[a]pyrene in humans. UPLC-accelerator mass spectrometry following oral microdosing.. Chem Biol Interact. 382:110608.
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Anderson KA, Tidwell LG, Tilton SC, Ognibene TJ, Turteltaub KW, Smith JN et al..  2022.  Benzo[a]pyrene (BaP) metabolites predominant in human plasma following escalating oral micro-dosing with [C]-BaP.. Environ Int. 159:107045.
Hummel JM, Madeen EP, Siddens LK, Uesugi SL, McQuistan T, Anderson KA, Turteltaub KW, Ognibene TJ, Bench G, Krueger SK et al..  2018.  Pharmacokinetics of [C]-Benzo[a]pyrene (BaP) in humans: Impact of Co-Administration of smoked salmon and BaP dietary restriction.. Food Chem Toxicol. 115:136-147.
Maier MLVermilli, Siddens LK, Pennington JM, Uesugi SL, Tilton SC, Vertel EA, Anderson KA, Tidwell LG, Ognibene TJ, Turteltaub KW et al..  2023.  Benzo[a]pyrene toxicokinetics in humans following dietary supplementation with 3,3'-diindolylmethane (DIM) or Brussels sprouts.. Toxicol Appl Pharmacol. 460:116377.
Benzopyrenes
Harper TA, Morré J, Lauer FT, McQuistan TJ, Hummel JM, Burchiel SW, Williams DE.  2015.  Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.. Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Williams DE.  2012.  The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.. Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Siddens LK, Bunde KL, Harper TA, McQuistan TJ, Löhr CV, Bramer LM, Waters KM, Tilton SC, Krueger SK, Williams DE et al..  2015.  Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.. Toxicol Appl Pharmacol. 287(2):149-160.
McQuistan TJ, Simonich MT, M Pratt M, Pereira CB, Hendricks JD, Dashwood RH, Williams DE, Bailey GS.  2012.  Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.. Food Chem Toxicol. 50(2):341-52.
Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS.  2008.  Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.. Food Chem Toxicol. 46(3):1014-24.
Bailey GS, Reddy AP, Pereira CB, Harttig U, Baird W, Spitsbergen JM, Hendricks JD, Orner GA, Williams DE, Swenberg JA.  2009.  Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.. Chem Res Toxicol. 22(7):1264-76.
beta Catenin
Wang R, W Dashwood M, Löhr CV, Fischer KA, Nakagama H, Williams DE, Dashwood RH.  2008.  beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.. Cancer Sci. 99(9):1754-9.
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.
beta-Naphthoflavone
Tilton SC, Givan SA, Pereira CB, Bailey GS, Williams DE.  2006.  Toxicogenomic profiling of the hepatic tumor promoters indole-3-carbinol, 17beta-estradiol and beta-naphthoflavone in rainbow trout.. Toxicol Sci. 90(1):61-72.
Biomarkers, Tumor
Bailey GS, Reddy AP, Pereira CB, Harttig U, Baird W, Spitsbergen JM, Hendricks JD, Orner GA, Williams DE, Swenberg JA.  2009.  Nonlinear cancer response at ultralow dose: a 40800-animal ED(001) tumor and biomarker study.. Chem Res Toxicol. 22(7):1264-76.
Biotransformation
Krueger SK, VanDyke JE, Williams DE, Hines RN.  2006.  The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines.. Drug Metab Rev. 38(1-2):139-47.
Blotting, Western
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Krueger SK, Martin SR, Yueh M-F, Pereira CB, Williams DE.  2002.  Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.. Drug Metab Dispos. 30(1):34-41.
Brain
Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.
Brassica
Bouranis JA, Beaver LM, Jiang D, Choi J, Wong CP, Davis EW, Williams DE, Sharpton TJ, Stevens JF, Ho E.  2022.  Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.. Nutrients. 15(1)
Brassicaceae
Higdon JV, Delage B, Williams DE, Dashwood RH.  2007.  Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.. Pharmacol Res. 55(3):224-36.
Caco-2 Cells
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Caffeine
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.

Pages