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Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Endothelin-2
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Endothelin-3
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Endothelins
Kacsóh B
,
Tóth BE
,
Avery LM
,
Grosvenor CE
. 1993.
In vitro control of prolactin (PRL) and growth hormone secretion of neonatal rat pituitary glands: effects of ovine PRL, salmon calcitonin, endothelin-3, angiotensin II, bromocryptine and somatostatin.
.
Life Sci. 52(3):259-69.
Endothelium, Vascular
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Mah E
,
Pei R
,
Guo Y
,
Masterjohn C
,
Ballard KD
,
Taylor BA
,
Taylor AW
,
Traber MG
,
Volek JS
,
Bruno RS
. 2015.
Greater γ-tocopherol status during acute smoking abstinence with nicotine replacement therapy improved vascular endothelial function by decreasing 8-iso-15(S)-prostaglandin F2α.
.
Exp Biol Med (Maywood). 240(4):527-33.
Carr A
,
Frei B
. 2000.
The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide.
.
Free Radic Biol Med. 28(12):1806-14.
Zhang WJian
,
Stocker R
,
McCall MR
,
Forte TM
,
Frei B
. 2002.
Lack of inhibitory effect of HDL on TNFalpha-induced adhesion molecule expression in human aortic endothelial cells.
.
Atherosclerosis. 165(2):241-9.
Zhang W-J
,
Frei B
. 2002.
Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.
.
Cardiovasc Res. 55(4):820-9.
Smith AR
,
Hagen TM
. 2003.
Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.
.
Biochem Soc Trans. 31(Pt 6):1447-9.
Smith AR
,
Visioli F
,
Hagen TM
. 2002.
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.
.
FASEB J. 16(9):1102-4.
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2008.
Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.
.
Br J Pharmacol. 153(8):1615-22.
Mah E
,
Pei R
,
Guo Y
,
Ballard KD
,
Barker T
,
Rogers VE
,
Parker BA
,
Taylor AW
,
Traber MG
,
Volek JS
et al.
. 2013.
γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation.
.
Free Radic Biol Med. 65:1291-1299.
Carr AC
,
McCall MR
,
Frei B
. 2000.
Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection.
.
Arterioscler Thromb Vasc Biol. 20(7):1716-23.
Endotoxemia
Traber MG
,
Buettner GR
,
Bruno RS
. 2019.
The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome.
.
Redox Biol. 21:101091.
Endotoxins
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
Energy Intake
Butler JA
,
Hagen TM
,
Moreau R
. 2009.
Lipoic acid improves hypertriglyceridemia by stimulating triacylglycerol clearance and downregulating liver triacylglycerol secretion.
.
Arch Biochem Biophys. 485(1):63-71.
Energy Metabolism
Finlay LA
,
Michels AJ
,
Butler JA
,
Smith EJ
,
Monette JS
,
Moreau RF
,
Petersen SKate
,
Frei B
,
Hagen TM
. 2012.
R-α-lipoic acid does not reverse hepatic inflammation of aging, but lowers lipid anabolism, while accentuating circadian rhythm transcript profiles.
.
Am J Physiol Regul Integr Comp Physiol. 302(5):R587-97.
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
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