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Phenylthiourea
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Philadelphia Chromosome
Tóth G
,
Jurka J
. 1994.
Repetitive DNA in and around translocation breakpoints of the Philadelphia chromosome.
.
Gene. 140(2):285-8.
Phosphatidylcholine-Sterol O-Acyltransferase
McCall MR
,
Carr AC
,
Forte TM
,
Frei B
. 2001.
Ldl modified by hypochlorous acid is a potent inhibitor of lecithin-cholesterol acyltransferase activity.
.
Arterioscler Thromb Vasc Biol. 21(6):1040-5.
Phosphatidylcholines
Kuschner CE
,
Choi J
,
Yin T
,
Shinozaki K
,
Becker LB
,
Lampe JW
,
Kim J
. 2018.
Comparing phospholipid profiles of mitochondria and whole tissue: Higher PUFA content in mitochondria is driven by increased phosphatidylcholine unsaturation.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1093-1094:147-157.
Phosphatidylinositol 3-Kinases
Zhang W-J
,
Wei H
,
Hagen T
,
Frei B
. 2007.
Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.
.
Proc Natl Acad Sci U S A. 104(10):4077-82.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Larsen CA
,
Dashwood RH
. 2010.
(-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells.
.
Arch Biochem Biophys. 501(1):52-7.
Phosphodiesterase I
Boulikas T
. 1992.
Poly(ADP-ribose) synthesis and degradation in mammalian nuclei.
.
Anal Biochem. 203(2):252-8.
Phospholipids
Kuschner CE
,
Choi J
,
Yin T
,
Shinozaki K
,
Becker LB
,
Lampe JW
,
Kim J
. 2018.
Comparing phospholipid profiles of mitochondria and whole tissue: Higher PUFA content in mitochondria is driven by increased phosphatidylcholine unsaturation.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1093-1094:147-157.
Choi J
,
Yin T
,
Shinozaki K
,
Lampe JW
,
Stevens JF
,
Becker LB
,
Kim J
. 2018.
Comprehensive analysis of phospholipids in the brain, heart, kidney, and liver: brain phospholipids are least enriched with polyunsaturated fatty acids.
.
Mol Cell Biochem. 442(1-2):187-201.
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
McDougall MQ
,
Choi J
,
Stevens JF
,
Truong L
,
Tanguay RL
,
Traber MG
. 2016.
Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos.
.
Redox Biol. 8:165-74.
Phosphoprotein Phosphatases
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Phosphoproteins
Zhang WJian
,
Frei B
. 2003.
Intracellular metal ion chelators inhibit TNFalpha-induced SP-1 activation and adhesion molecule expression in human aortic endothelial cells.
.
Free Radic Biol Med. 34(6):674-82.
Phosphoric Diester Hydrolases
Boulikas T
. 1992.
Poly(ADP-ribose) synthesis and degradation in mammalian nuclei.
.
Anal Biochem. 203(2):252-8.
Phosphorus Radioisotopes
Boulikas T
. 1992.
Poly(ADP-ribose) synthesis in blocked and damaged cells and its relation to carcinogenesis.
.
Anticancer Res. 12(3):885-98.
Phosphorylation
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
Harris RA
,
Hagen TM
. 2004.
Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.
.
Biochem Biophys Res Commun. 325(1):48-58.
Smith AR
,
Hagen TM
. 2003.
Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.
.
Biochem Soc Trans. 31(Pt 6):1447-9.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2008.
Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.
.
Br J Pharmacol. 153(8):1615-22.
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Photobiology
Carpenter EL
,
Wyant MB
,
Indra A
,
Ito S
,
Wakamatsu K
,
Merrill GF
,
Moos PJ
,
Cassidy PB
,
Leachman SA
,
Ganguli-Indra G
et al.
. 2022.
Thioredoxin Reductase 1 Modulates Pigmentation and Photobiology of Murine Melanocytes in vivo.
.
J Invest Dermatol. 142(7):1903-1911.e5.
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