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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
Found 909 results
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Dashwood, Roderick H
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Cadherins
Dashwood W-M
,
Carter O
,
Al-Fageeh M
,
Li Q
,
Dashwood RH
. 2005.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
.
Mutat Res. 591(1-2):161-72.
Caco-2 Cells
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Butyrates
Myzak MC
,
Dashwood RH
. 2006.
Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.
.
Curr Drug Targets. 7(4):443-52.
Brassicaceae
Higdon JV
,
Delage B
,
Williams DE
,
Dashwood RH
. 2007.
Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.
.
Pharmacol Res. 55(3):224-36.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Body Weight
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Blotting, Western
Li Q
,
Löhr CV
,
Dashwood RH
. 2009.
Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
.
Cancer Lett. 283(1):36-42.
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Biomarkers
Carter O
,
Bailey GS
,
Dashwood RH
. 2004.
The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
.
J Nutr. 134(12 Suppl):3441S-3444S.
Binding, Competitive
Nian H
,
Delage B
,
Pinto JT
,
Dashwood RH
. 2008.
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.
.
Carcinogenesis. 29(9):1816-24.
Binding Sites
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
beta-Galactosidase
Dashwood RH
. 2003.
Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.
.
J Biochem Mol Biol. 36(1):35-42.
beta Catenin
Li Q
,
Dashwood RH
. 2004.
Activator protein 2alpha associates with adenomatous polyposis coli/beta-catenin and Inhibits beta-catenin/T-cell factor transcriptional activity in colorectal cancer cells.
.
J Biol Chem. 279(44):45669-75.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Dashwood W-M
,
Carter O
,
Al-Fageeh M
,
Li Q
,
Dashwood RH
. 2005.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
.
Mutat Res. 591(1-2):161-72.
Li Q
,
Dixon BM
,
Al-Fageeh M
,
Blum CA
,
Dashwood RH
. 2002.
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
.
Gene. 283(1-2):255-62.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.
.
Carcinogenesis. 24(2):263-7.
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Blum CA
,
Xu M
,
Orner GA
,
G Díaz D
,
Li Q
,
Dashwood WMohaiza
,
Bailey GS
,
Dashwood RH
. 2003.
Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.
.
Mutat Res. 523-524:217-23.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Carter O
,
Bailey GS
,
Dashwood RH
. 2004.
The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.
.
J Nutr. 134(12 Suppl):3441S-3444S.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Pereira CB
,
Louderback M
,
Nakagama H
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2008.
Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.
.
Carcinogenesis. 29(4):834-9.
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
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