Linus Pauling Institute

Mustacich DJ, Leonard SW, Devereaux MW, Sokol RJ, Traber MG.  2006.  Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.. Free Radic Biol Med. 41(7):1069-78.

Traber MG, Siddens LK, Leonard SW, Schock B, Gohil K, Krueger SK, Cross CE, Williams DE.  2005.  Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.. Free Radic Biol Med. 38(6):773-85.

Traber MG, Cross CE.  2023.  Alpha-Tocopherol from People to Plants Is an Essential Cog in the Metabolic Machinery.. Antioxid Redox Signal. 38(10-12):775-791.

Mustacich DJ, Leonard SW, Patel NK, Traber MG.  2010.  Alpha-tocopherol beta-oxidation localized to rat liver mitochondria.. Free Radic Biol Med. 48(1):73-81.

Wagener BM, Anjum N, Evans C, Brandon A, Honavar J, Creighton J, Traber MG, Stuart RL, Stevens T, Pittet J-F.  2020.  Alpha-tocopherol Attenuates the Severity of -induced Pneumonia.. Am J Respir Cell Mol Biol.

Zhang WJ, Frei B.  2001.  Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.. FASEB J. 15(13):2423-32.

Zhang W-J, Wei H, Hagen T, Frei B.  2007.  Alpha-lipoic acid attenuates LPS-induced inflammatory responses by activating the phosphoinositide 3-kinase/Akt signaling pathway.. Proc Natl Acad Sci U S A. 104(10):4077-82.

Shay KPetersen, Moreau RF, Smith EJ, Smith AR, Hagen TM.  2009.  Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.. Biochim Biophys Acta. 1790(10):1149-60.

Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.

Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.

Gazit E, Gothelf Y, Gil R, Orgad S, Pitman TB, Watson AL, Yang SY, Yunis EJ.  1984.  Alloantibodies to PHA-activated lymphocytes detect human Qa-like antigens.. J Immunol. 132(1):165-9.

Zhang W-J, Frei B.  2002.  Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.. Cardiovasc Res. 55(4):820-9.

Ehrlich AK, Pennington JM, Tilton S, Wang X, Marshall NB, Rohlman D, Funatake C, Punj S, O'Donnell E, Yu Z et al..  2017.  AhR activation increases IL-2 production by alloreactive CD4 T cells initiating the differentiation of mucosal-homing Tim3 Lag3 Tr1 cells.. Eur J Immunol. 47(11):1989-2001.

Magnusson KR.  2012.  Aging of the NMDA receptor: from a mouse's point of view.. Future Neurol. 7(5):627-637.

Sunchu B, Riordan RT, Yu Z, Almog I, Dimas-Munoz J, Drake AC, Perez VI.  2020.  Aggresome-Like Formation Promotes Resistance to Proteotoxicity in Cells from Long-Lived Species.. J Gerontol A Biol Sci Med Sci. 75(8):1439-1447.

Leinweber B, Barofsky E, Barofsky DF, Ermilov V, Nylin K, Beckman JS.  2004.  Aggregation of ALS mutant superoxide dismutase expressed in Escherichia coli.. Free Radic Biol Med. 36(7):911-8.

Thomas NO, Shay KP, Hagen TM.  2019.  Age-related loss of mitochondrial glutathione exacerbates menadione-induced inhibition of Complex I.. Redox Biol. 22:101155.

Smith EJ, Shay KP, Thomas NO, Butler JA, Finlay LF, Hagen TM.  2015.  Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.. Free Radic Biol Med. 89:1184-91.

Moreau R, Heath S-HD, Doneanu CE, J Lindsay G, Hagen TM.  2003.  Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.. Antioxid Redox Signal. 5(5):517-27.

Reynolds NC, Zhong JY, Clendinen CA, Moffat SD, Magnusson KR.  2019.  Age-related differences in brain activations during spatial memory formation in a well-learned virtual Morris water maze (vMWM) task.. Neuroimage. 202:116069.

Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.

Gómez LA, Hagen TM.  2012.  Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production? Semin Cell Dev Biol. 23(7):758-67.

Moreau R, Heath S-HD, Doneanu CE, Harris RA, Hagen TM.  2004.  Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.. Biochem Biophys Res Commun. 325(1):48-58.

Smith AR, Visioli F, Frei B, Hagen TM.  2006.  Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.. Aging Cell. 5(5):391-400.

Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.