Found 909 results
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Filters: Author is Dashwood, Roderick H  [Clear All Filters]
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Anticarcinogenic Agents
Dashwood W-M, Orner GA, Dashwood RH.  2002.  Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations.. Biochem Biophys Res Commun. 296(3):584-8.
Wang R, W Dashwood M, Löhr CV, Fischer KA, Pereira CB, Louderback M, Nakagama H, Bailey GS, Williams DE, Dashwood RH.  2008.  Protective versus promotional effects of white tea and caffeine on PhIP-induced tumorigenesis and beta-catenin expression in the rat.. Carcinogenesis. 29(4):834-9.
Dashwood RH.  2002.  Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.. Mutat Res. 511(2):89-112.
Myzak MC, Dashwood RH.  2006.  Chemoprotection by sulforaphane: keep one eye beyond Keap1.. Cancer Lett. 233(2):208-18.
Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang JH, Löhr CV, Williams DE et al..  2017.  Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.. J Nutr Biochem. 42:72-83.
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.
Higdon JV, Delage B, Williams DE, Dashwood RH.  2007.  Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis.. Pharmacol Res. 55(3):224-36.
Myzak MC, P Karplus A, Chung F-L, Dashwood RH.  2004.  A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.. Cancer Res. 64(16):5767-74.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Anti-Inflammatory Agents, Non-Steroidal
Orner GA, Dashwood W-M, Blum CA, G Díaz D, Li Q, Al-Fageeh M, Tebbutt N, Heath JK, Ernst M, Dashwood RH.  2002.  Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).. Mutat Res. 506-507:121-7.
Mastaloudis A, Yu T-W, O'Donnell RP, Frei B, Dashwood RH, Traber MG.  2004.  Endurance exercise results in DNA damage as detected by the comet assay.. Free Radic Biol Med. 36(8):966-75.
Orner GA, Dashwood W-M, Blum CA, G Díaz D, Li Q, Dashwood RH.  2003.  Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.. Carcinogenesis. 24(2):263-7.
Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.
Animals, Genetically Modified
Dashwood RH.  2002.  Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.. Mutat Res. 511(2):89-112.
Animals
Al-Fageeh M, Li Q, W Dashwood M, Myzak MC, Dashwood RH.  2004.  Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.. Oncogene. 23(28):4839-46.
Delage B, Dashwood RH.  2008.  Dietary manipulation of histone structure and function.. Annu Rev Nutr. 28:347-66.
Li Q, Dixon BM, Al-Fageeh M, Blum CA, Dashwood RH.  2002.  Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.. Gene. 283(1-2):255-62.
Larsen CA, Dashwood RH, Bisson WH.  2010.  Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.. Pharmacol Res. 62(6):457-64.
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.
Orner GA, Dashwood W-M, Dashwood RH.  2004.  Tumor-suppressing effects of antioxidants from tea.. J Nutr. 134(11):3177S-3178S.
Li Q, Dashwood W-M, Zhong X, Al-Fageeh M, Dashwood RH.  2004.  Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.. Genomics. 83(2):231-42.
Wang R, Kang Y, Löhr CV, Fischer KA, C Bradford S, Johnson G, Dashwood WMohaiza, Williams DE, Ho E, Dashwood RH.  2016.  Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.. Cancer Lett. 381(2):341-8.
Myzak MC, Dashwood RH.  2006.  Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and sulforaphane.. Curr Drug Targets. 7(4):443-52.

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