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Dashwood, Roderick H
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Anticarcinogenic Agents
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Myzak MC
,
Dashwood RH
. 2006.
Chemoprotection by sulforaphane: keep one eye beyond Keap1.
.
Cancer Lett. 233(2):208-18.
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Dashwood W-M
,
Carter O
,
Al-Fageeh M
,
Li Q
,
Dashwood RH
. 2005.
Lysosomal trafficking of beta-catenin induced by the tea polyphenol epigallocatechin-3-gallate.
.
Mutat Res. 591(1-2):161-72.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Larsen CA
,
Dashwood RH
,
Bisson WH
. 2010.
Tea catechins as inhibitors of receptor tyrosine kinases: mechanistic insights and human relevance.
.
Pharmacol Res. 62(6):457-64.
Myzak MC
,
Hardin K
,
Wang R
,
Dashwood RH
,
Ho E
. 2006.
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.
.
Carcinogenesis. 27(4):811-9.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Myzak MC
,
P Karplus A
,
Chung F-L
,
Dashwood RH
. 2004.
A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.
.
Cancer Res. 64(16):5767-74.
Anti-Inflammatory Agents, Non-Steroidal
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Mastaloudis A
,
Yu T-W
,
O'Donnell RP
,
Frei B
,
Dashwood RH
,
Traber MG
. 2004.
Endurance exercise results in DNA damage as detected by the comet assay.
.
Free Radic Biol Med. 36(8):966-75.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Suppression of tumorigenesis in the Apc(min) mouse: down-regulation of beta-catenin signaling by a combination of tea plus sulindac.
.
Carcinogenesis. 24(2):263-7.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Animals, Genetically Modified
Dashwood RH
. 2002.
Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.
.
Mutat Res. 511(2):89-112.
Animals
Li Q
,
Löhr CV
,
Dashwood RH
. 2009.
Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.
.
Cancer Lett. 283(1):36-42.
Dashwood RH
. 2002.
Modulation of heterocyclic amine-induced mutagenicity and carcinogenicity: an 'A-to-Z' guide to chemopreventive agents, promoters, and transgenic models.
.
Mutat Res. 511(2):89-112.
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
Al-Fageeh M
,
Li Q
,
W Dashwood M
,
Myzak MC
,
Dashwood RH
. 2004.
Phosphorylation and ubiquitination of oncogenic mutants of beta-catenin containing substitutions at Asp32.
.
Oncogene. 23(28):4839-46.
Dashwood RH
,
Ho E
. 2008.
Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.
.
Nutr Rev. 66 Suppl 1:S36-8.
Simonich MT
,
McQuistan T
,
Jubert C
,
Pereira C
,
Hendricks JD
,
Schimerlik M
,
Zhu B
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2008.
Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.
.
Food Chem Toxicol. 46(3):1014-24.
Li Q
,
Dixon BM
,
Al-Fageeh M
,
Blum CA
,
Dashwood RH
. 2002.
Sequencing of the rat beta-catenin gene (Ctnnb1) and mutational analysis of liver tumors induced by 2-amino-3-methylimidazo[4,5-f]quinoline.
.
Gene. 283(1-2):255-62.
Parasramka MA
,
Ho E
,
Williams DE
,
Dashwood RH
. 2012.
MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.
.
Mol Carcinog. 51(3):213-30.
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
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