Linus Pauling Institute

Kesinger NG, Langsdorf BL, Yokochi AF, Miranda CL, Stevens JF.  2010.  Formation of a vitamin C conjugate of acrolein and its paraoxonase-mediated conversion into 5,6,7,8-tetrahydroxy-4-oxooctanal.. Chem Res Toxicol. 23(4):836-44.

Zhang WJ, Frei B.  2001.  Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.. FASEB J. 15(13):2423-32.

Tsao CS.  1991.  Inhibiting effect of ascorbic acid on the growth of human mammary tumor xenografts.. Am J Clin Nutr. 54(6 Suppl):1274S-1280S.

Traber MG, Leonard SW, Vasu VT, Morrissey BM, Lei HJohn, Atkinson J, Cross CE.  2022.  α-Tocopherol Pharmacokinetics in Adults with Cystic Fibrosis: Benefits of Supplemental Vitamin C Administration.. Nutrients. 14(18)

Carr AC, Gombart AF.  2022.  Multi-Level Immune Support by Vitamins C and D during the SARS-CoV-2 Pandemic.. Nutrients. 14(3)

Lotito SB, Frei B.  2004.  The increase in human plasma antioxidant capacity after apple consumption is due to the metabolic effect of fructose on urate, not apple-derived antioxidant flavonoids.. Free Radic Biol Med. 37(2):251-8.

Myzak MC, Carr AC.  2002.  Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid.. Redox Rep. 7(1):47-53.

Durst RW, Weaver GW.  2013.  Nutritional content of fresh and canned peaches.. J Sci Food Agric. 93(3):593-603.

Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF.  2012.  Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.. J Biol Chem. 287(6):3833-41.

Pauling L.  1991.  Effect of ascorbic acid on incidence of spontaneous mammary tumors and UV-light-induced skin tumors in mice.. Am J Clin Nutr. 54(6 Suppl):1252S-1255S.

Michels AJ, Joisher N, Hagen TM.  2003.  Age-related decline of sodium-dependent ascorbic acid transport in isolated rat hepatocytes.. Arch Biochem Biophys. 410(1):112-20.

Lebold KM, Löhr CV, Barton CL, Miller GW, Labut EM, Tanguay RL, Traber MG.  2013.  Chronic vitamin E deficiency promotes vitamin C deficiency in zebrafish leading to degenerative myopathy and impaired swimming behavior.. Comp Biochem Physiol C Toxicol Pharmacol. 157(4):382-9.

Harakeh S, Jariwalla RJ.  1991.  Comparative study of the anti-HIV activities of ascorbate and thiol-containing reducing agents in chronically HIV-infected cells.. Am J Clin Nutr. 54(6 Suppl):1231S-1235S.

Visioli F, Smith A, Zhang W, Keaney JF, Hagen T, Frei B.  2002.  Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.. Redox Rep. 7(4):223-7.

Leung PY, Miyashita K, Young M, Tsao CS.  1993.  Cytotoxic effect of ascorbate and its derivatives on cultured malignant and nonmalignant cell lines.. Anticancer Res. 13(2):475-80.

Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.

Cameron E.  1991.  Protocol for the use of vitamin C in the treatment of cancer.. Med Hypotheses. 36(3):190-4.

Carr A, Frei B.  2000.  The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide.. Free Radic Biol Med. 28(12):1806-14.

Harakeh S, Jariwalla RJ.  1995.  Ascorbate effect on cytokine stimulation of HIV production.. Nutrition. 11(5 Suppl):684-7.

Carr AC, Decker EA, Park Y, Frei B.  2001.  Comparison of low-density lipoprotein modification by myeloperoxidase-derived hypochlorous and hypobromous acids.. Free Radic Biol Med. 31(1):62-72.

Kirkwood JS, Lebold KM, Miranda CL, Wright CL, Miller GW, Tanguay RL, Barton CL, Traber MG, Stevens JF.  2012.  Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.. J Biol Chem. 287(6):3833-41.

Roomi MW, Ogg M, Tsao CS, Gibson GG.  1997.  Ascorbic acid deficiency decreases the expression of CYP4A1 in liver microsomes of guinea pigs.. Res Commun Mol Pathol Pharmacol. 95(1):3-10.

Michels AJ, Frei B.  2013.  Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research.. Nutrients. 5(12):5161-92.

Roomi MW.  1997.  Association between hyperlipidemia and hepatic cytochrome P-450 in guinea pigs.. Res Commun Mol Pathol Pharmacol. 97(2):139-50.

Lebold KM, Löhr CV, Barton CL, Miller GW, Labut EM, Tanguay RL, Traber MG.  2013.  Chronic vitamin E deficiency promotes vitamin C deficiency in zebrafish leading to degenerative myopathy and impaired swimming behavior.. Comp Biochem Physiol C Toxicol Pharmacol. 157(4):382-9.