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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Hagen, Tory M
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Brain
Suh JH
,
Moreau R
,
Heath S-HD
,
Hagen TM
. 2005.
Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.
.
Redox Rep. 10(1):52-60.
Cardiovascular System
Moreau R
,
Nguyen BT
,
Doneanu CE
,
Hagen TM
. 2005.
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats.
.
Biochem Pharmacol. 69(1):29-40.
Carnitine
Gómez LA
,
Heath S-HD
,
Hagen TM
. 2012.
Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.
.
Mech Ageing Dev. 133(2-3):99-106.
Carnitine O-Palmitoyltransferase
Gómez LA
,
Heath S-HD
,
Hagen TM
. 2012.
Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heart.
.
Mech Ageing Dev. 133(2-3):99-106.
Catalysis
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Cell Compartmentation
Shay KPetersen
,
Michels AJ
,
Li W
,
Kong A-NTony
,
Hagen TM
. 2012.
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
.
Biochim Biophys Acta. 1823(6):1102-9.
Cell Culture Techniques
Smith AR
,
Visioli F
,
Hagen TM
. 2002.
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.
.
FASEB J. 16(9):1102-4.
Cell Line, Tumor
Shenvi SV
,
Smith EJ
,
Hagen TM
. 2009.
Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.
.
Pharmacol Res. 60(4):229-36.
Cell Membrane
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Cell Nucleus
Shay KPetersen
,
Smith EJ
,
Hagen TM
. 2010.
Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).
.
Curr Protoc Toxicol. Chapter 17:Unit17.13.
Shay KPetersen
,
Michels AJ
,
Li W
,
Kong A-NTony
,
Hagen TM
. 2012.
Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response.
.
Biochim Biophys Acta. 1823(6):1102-9.
Cell Respiration
Rodríguez E
,
Radke A
,
Hagen TM
,
Blier PU
. 2022.
Supercomplex Organization of the Electron Transfer System in Marine Bivalves, a Model of Extreme Longevity.
.
J Gerontol A Biol Sci Med Sci. 77(2):283-290.
Cell Survival
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Cells, Cultured
Smith AR
,
Visioli F
,
Hagen TM
. 2002.
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.
.
FASEB J. 16(9):1102-4.
Shay KPetersen
,
Hagen TM
. 2009.
Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.
.
Biogerontology. 10(4):443-56.
Shay KPetersen
,
Smith EJ
,
Hagen TM
. 2010.
Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).
.
Curr Protoc Toxicol. Chapter 17:Unit17.13.
Robinson KM
,
Janes MS
,
Pehar M
,
Monette JS
,
Ross MF
,
Hagen TM
,
Murphy MP
,
Beckman JS
. 2006.
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.
.
Proc Natl Acad Sci U S A. 103(41):15038-43.
Shenvi SV
,
Smith EJ
,
Hagen TM
. 2009.
Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.
.
Pharmacol Res. 60(4):229-36.
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Smith EJ
,
Shay KP
,
Thomas NO
,
Butler JA
,
Finlay LF
,
Hagen TM
. 2015.
Age-related loss of hepatic Nrf2 protein homeostasis: Potential role for heightened expression of miR-146a.
.
Free Radic Biol Med. 89:1184-91.
Ceramides
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Cerebral Cortex
Suh JH
,
Moreau R
,
Heath S-HD
,
Hagen TM
. 2005.
Dietary supplementation with (R)-alpha-lipoic acid reverses the age-related accumulation of iron and depletion of antioxidants in the rat cerebral cortex.
.
Redox Rep. 10(1):52-60.
Cholesterol
Zhang W-J
,
Bird KE
,
McMillen TS
,
Leboeuf RC
,
Hagen TM
,
Frei B
. 2008.
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
.
Circulation. 117(3):421-8.
Chromatin Immunoprecipitation
Shay KPetersen
,
Smith EJ
,
Hagen TM
. 2010.
Transcription factor Nrf2: examination of nuclear protein levels by immunoblotting and promoter response element binding by chromatin immunoprecipitation (ChIP).
.
Curr Protoc Toxicol. Chapter 17:Unit17.13.
Shenvi SV
,
Smith EJ
,
Hagen TM
. 2009.
Transcriptional regulation of rat gamma-glutamate cysteine ligase catalytic subunit gene is mediated through a distal antioxidant response element.
.
Pharmacol Res. 60(4):229-36.
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