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Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Gombart, Adrian F
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Pandemics
Carr AC
,
Gombart AF
. 2022.
Multi-Level Immune Support by Vitamins C and D during the SARS-CoV-2 Pandemic.
.
Nutrients. 14(3)
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Eggersdorfer M
,
Berger MM
,
Calder PC
,
Gombart AF
,
Ho E
,
Laviano A
,
Meydani SN
. 2022.
Perspective: Role of Micronutrients and Omega-3 Long-Chain Polyunsaturated Fatty Acids for Immune Outcomes of Relevance to Infections in Older Adults-A Narrative Review and Call for Action.
.
Adv Nutr. 13(5):1415-1430.
p38 Mitogen-Activated Protein Kinases
Guo C
,
Sinnott B
,
Niu B
,
Lowry MB
,
Fantacone ML
,
Gombart AF
. 2014.
Synergistic induction of human cathelicidin antimicrobial peptide gene expression by vitamin D and stilbenoids.
.
Mol Nutr Food Res. 58(3):528-536.
Osteoclasts
Lowry MB
,
Guo C
,
Borregaard N
,
Gombart AF
. 2014.
Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.
.
J Steroid Biochem Mol Biol. 143:183-91.
Nutritional Status
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Nutritional Physiological Phenomena
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Neutrophils
Lowry MB
,
Guo C
,
Borregaard N
,
Gombart AF
. 2014.
Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.
.
J Steroid Biochem Mol Biol. 143:183-91.
Nanotechnology
Chen S
,
Liu B
,
Carlson MA
,
Gombart AF
,
Reilly DA
,
Xie J
. 2017.
Recent advances in electrospun nanofibers for wound healing.
.
Nanomedicine (Lond). 12(11):1335-1352.
Nanofibers
Su Y
,
Ganguli-Indra G
,
Bhattacharya N
,
Logan IE
,
Indra AK
,
Gombart AF
,
Wong SL
,
Xie J
. 2022.
Codelivery of 1α,25-Dihydroxyvitamin D and CYP24A1 Inhibitor VID400 by Nanofiber Dressings Promotes Endogenous Antimicrobial Peptide LL-37 Induction.
.
Mol Pharm. 19(3):974-984.
Jiang J
,
Chen S
,
Wang H
,
Carlson MA
,
Gombart AF
,
Xie J
. 2018.
CO-expanded nanofiber scaffolds maintain activity of encapsulated bioactive materials and promote cellular infiltration and positive host response.
.
Acta Biomater. 68:237-248.
Chen S
,
Liu B
,
Carlson MA
,
Gombart AF
,
Reilly DA
,
Xie J
. 2017.
Recent advances in electrospun nanofibers for wound healing.
.
Nanomedicine (Lond). 12(11):1335-1352.
Jiang J
,
Zhang Y
,
Indra AK
,
Ganguli-Indra G
,
Le MN
,
Wang H
,
Hollins RR
,
Reilly DA
,
Carlson MA
,
Gallo RL
et al.
. 2018.
1α,25-dihydroxyvitamin D-eluting nanofibrous dressings induce endogenous antimicrobial peptide expression.
.
Nanomedicine (Lond). 13(12):1417-1432.
Myeloid Cells
Guo C
,
Rosoha E
,
Lowry MB
,
Borregaard N
,
Gombart AF
. 2013.
Curcumin induces human cathelicidin antimicrobial peptide gene expression through a vitamin D receptor-independent pathway.
.
J Nutr Biochem. 24(5):754-9.
Monocytes
Lowry MB
,
Guo C
,
Borregaard N
,
Gombart AF
. 2014.
Regulation of the human cathelicidin antimicrobial peptide gene by 1α,25-dihydroxyvitamin D3 in primary immune cells.
.
J Steroid Biochem Mol Biol. 143:183-91.
Jiang J
,
Zhang Y
,
Indra AK
,
Ganguli-Indra G
,
Le MN
,
Wang H
,
Hollins RR
,
Reilly DA
,
Carlson MA
,
Gallo RL
et al.
. 2018.
1α,25-dihydroxyvitamin D-eluting nanofibrous dressings induce endogenous antimicrobial peptide expression.
.
Nanomedicine (Lond). 13(12):1417-1432.
Molecular Sequence Data
Gombart AF
,
Saito T
,
H Koeffler P
. 2009.
Exaptation of an ancient Alu short interspersed element provides a highly conserved vitamin D-mediated innate immune response in humans and primates.
.
BMC Genomics. 10:321.
Molecular Dynamics Simulation
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Molecular Docking Simulation
Yang L
,
Broderick D
,
Campbell Y
,
Gombart AF
,
Stevens JF
,
Jiang Y
,
Hsu VL
,
Bisson WH
,
Maier CS
. 2016.
Conformational modulation of the farnesoid X receptor by prenylflavonoids: Insights from hydrogen deuterium exchange mass spectrometry (HDX-MS), fluorescence titration and molecular docking studies.
.
Biochim Biophys Acta. 1864(12):1667-1677.
Micronutrients
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Eggersdorfer M
,
Berger MM
,
Calder PC
,
Gombart AF
,
Ho E
,
Laviano A
,
Meydani SN
. 2022.
Perspective: Role of Micronutrients and Omega-3 Long-Chain Polyunsaturated Fatty Acids for Immune Outcomes of Relevance to Infections in Older Adults-A Narrative Review and Call for Action.
.
Adv Nutr. 13(5):1415-1430.
Calder PC
,
Carr AC
,
Gombart AF
,
Eggersdorfer M
. 2020.
Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.
.
Nutrients. 12(4)
Mice, Transgenic
Lowry MB
,
Guo C
,
Zhang Y
,
Fantacone ML
,
Logan IE
,
Campbell Y
,
Zhang W
,
Le M
,
Indra AK
,
Ganguli-Indra G
et al.
. 2020.
A mouse model for vitamin D-induced human cathelicidin antimicrobial peptide gene expression.
.
J Steroid Biochem Mol Biol. 198:105552.
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