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Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Energy Metabolism
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
Michels AJ
,
Butler JA
,
Uesugi SL
,
Lee K
,
Frei BB
,
Bobe G
,
Magnusson KR
,
Hagen TM
. 2023.
Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study.
.
Nutrients. 15(12)
Gómez LA
,
Hagen TM
. 2012.
Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?
Semin Cell Dev Biol. 23(7):758-67.
McDougall M
,
Choi J
,
Kim H-K
,
Bobe G
,
J Stevens F
,
Cadenas E
,
Tanguay R
,
Traber MG
. 2017.
Lethal dysregulation of energy metabolism during embryonic vitamin E deficiency.
.
Free Radic Biol Med. 104:324-332.
Enhancer of Zeste Homolog 2 Protein
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Enterobacteriaceae
Bouranis JA
,
Beaver LM
,
Choi J
,
Wong CP
,
Jiang D
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2021.
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.
.
Nutrients. 13(9)
Enterohepatic Circulation
Rubinstein I
,
van Breemen R
,
Nosal DG
,
Weinberg G
,
Hershow RC
,
Feinstein DL
. 2019.
Should Cytochrome P450 Inducers be Used to Accelerate Clearance of Brodifacoum from Poisoned Patients?
Drugs R D. 19(1):67-71.
Environment
Watts EJ
,
Shen Y
,
Lansky EP
,
Nevo E
,
Bobe G
,
Traber MG
. 2015.
High environmental stress yields greater tocotrienol content while changing vitamin e profiles of wild emmer wheat seeds.
.
J Med Food. 18(2):216-23.
Environmental Exposure
Williams DE
. 2012.
The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
.
Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Enzyme Activation
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Myzak MC
,
Carr AC
. 2002.
Myeloperoxidase-dependent caspase-3 activation and apoptosis in HL-60 cells: protection by the antioxidants ascorbate and (dihydro)lipoic acid.
.
Redox Rep. 7(1):47-53.
G Díaz D
,
Li Q
,
Dashwood RH
. 2003.
Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.
.
Cancer Res. 63(6):1254-61.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
Harris RA
,
Hagen TM
. 2004.
Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.
.
Biochem Biophys Res Commun. 325(1):48-58.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
Enzyme Induction
Katchamart S
,
Williams DE
. 2001.
Indole-3-carbinol modulation of hepatic monooxygenases CYP1A1, CYP1A2 and FMO1 in guinea pig, mouse and rabbit.
.
Comp Biochem Physiol C Toxicol Pharmacol. 129(4):377-84.
Williams DE
,
Katchamar S
,
Larsen-Su SA
,
Stresser DM
,
Dehal SS
,
Kupfer D
. 2001.
Concurrent flavin-containing monooxygenase down regulation and cytochrome P450 induction by dietary indoles in the rat: implication for drug-drug interactions.
.
Adv Exp Med Biol. 500:635-8.
Roomi MW
. 1997.
Association between hyperlipidemia and hepatic cytochrome P-450 in guinea pigs.
.
Res Commun Mol Pathol Pharmacol. 97(2):139-50.
Miller MS
,
Buzard GS
,
McDowell AE
. 1993.
In vivo inhibition of glucocorticoid-inducible gene expression by dimethylnitrosamine in rat liver.
.
Biochem Pharmacol. 45(7):1465-70.
Enzyme Inhibitors
Myzak MC
,
Ho E
,
Dashwood RH
. 2006.
Dietary agents as histone deacetylase inhibitors.
.
Mol Carcinog. 45(6):443-6.
Moreau R
,
Heath S-HD
,
Doneanu CE
,
J Lindsay G
,
Hagen TM
. 2003.
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity.
.
Antioxid Redox Signal. 5(5):517-27.
Yilmazer-Musa M
,
Griffith AM
,
Michels AJ
,
Schneider E
,
Frei B
. 2012.
Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity.
.
J Agric Food Chem. 60(36):8924-9.
Kubglomsong S
,
Theerakulkait C
,
Reed RL
,
Yang L
,
Maier CS
,
Stevens JF
. 2018.
Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.
.
J Agric Food Chem. 66(31):8346-8354.
Dixon BM
,
Heath S-HD
,
Kim R
,
Suh JH
,
Hagen TM
. 2008.
Assessment of endoplasmic reticulum glutathione redox status is confounded by extensive ex vivo oxidation.
.
Antioxid Redox Signal. 10(5):963-72.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
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