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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Endothelium, Vascular
Smith AR
,
Hagen TM
. 2003.
Vascular endothelial dysfunction in aging: loss of Akt-dependent endothelial nitric oxide synthase phosphorylation and partial restoration by (R)-alpha-lipoic acid.
.
Biochem Soc Trans. 31(Pt 6):1447-9.
Smith AR
,
Visioli F
,
Hagen TM
. 2006.
Plasma membrane-associated endothelial nitric oxide synthase and activity in aging rat aortic vascular endothelia markedly decline with age.
.
Arch Biochem Biophys. 454(1):100-5.
Smith AR
,
Visioli F
,
Hagen TM
. 2002.
Vitamin C matters: increased oxidative stress in cultured human aortic endothelial cells without supplemental ascorbic acid.
.
FASEB J. 16(9):1102-4.
Lotito SB
,
Frei B
. 2006.
Dietary flavonoids attenuate tumor necrosis factor alpha-induced adhesion molecule expression in human aortic endothelial cells. Structure-function relationships and activity after first pass metabolism.
.
J Biol Chem. 281(48):37102-10.
Zhang WJ
,
Frei B
. 2001.
Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells.
.
FASEB J. 15(13):2423-32.
Visioli F
,
Smith A
,
Zhang W
,
Keaney JF
,
Hagen T
,
Frei B
. 2002.
Lipoic acid and vitamin C potentiate nitric oxide synthesis in human aortic endothelial cells independently of cellular glutathione status.
.
Redox Rep. 7(4):223-7.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2006.
Age-related changes in endothelial nitric oxide synthase phosphorylation and nitric oxide dependent vasodilation: evidence for a novel mechanism involving sphingomyelinase and ceramide-activated phosphatase 2A.
.
Aging Cell. 5(5):391-400.
Carr AC
,
Zhu BZ
,
Frei B
. 2000.
Potential antiatherogenic mechanisms of ascorbate (vitamin C) and alpha-tocopherol (vitamin E).
.
Circ Res. 87(5):349-54.
Smith AR
,
Visioli F
,
Frei B
,
Hagen TM
. 2008.
Lipoic acid significantly restores, in rats, the age-related decline in vasomotion.
.
Br J Pharmacol. 153(8):1615-22.
Mah E
,
Pei R
,
Guo Y
,
Ballard KD
,
Barker T
,
Rogers VE
,
Parker BA
,
Taylor AW
,
Traber MG
,
Volek JS
et al.
. 2013.
γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation.
.
Free Radic Biol Med. 65:1291-1299.
Carr AC
,
McCall MR
,
Frei B
. 2000.
Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection.
.
Arterioscler Thromb Vasc Biol. 20(7):1716-23.
Endothelins
Kacsóh B
,
Tóth BE
,
Avery LM
,
Grosvenor CE
. 1993.
In vitro control of prolactin (PRL) and growth hormone secretion of neonatal rat pituitary glands: effects of ovine PRL, salmon calcitonin, endothelin-3, angiotensin II, bromocryptine and somatostatin.
.
Life Sci. 52(3):259-69.
Endothelin-3
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Endothelin-2
Wang R
,
Löhr CV
,
Fischer K
,
W Dashwood M
,
Greenwood JA
,
Ho E
,
Williams DE
,
Ashktorab H
,
Dashwood MR
,
Dashwood RH
. 2013.
Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.
.
Int J Cancer. 132(5):1004-12.
Endothelial Cells
Li C
,
Zhang W-J
,
Frei B
. 2016.
Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction.
.
Redox Biol. 9:104-113.
Li L
,
Frei B
. 2009.
Prolonged exposure to LPS increases iron, heme, and p22phox levels and NADPH oxidase activity in human aortic endothelial cells: inhibition by desferrioxamine.
.
Arterioscler Thromb Vasc Biol. 29(5):732-8.
Li C
,
Zhang W-J
,
Choi J
,
Frei B
. 2016.
Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.
.
Redox Biol. 9:220-228.
Axton ER
,
Hardardt EA
,
Stevens JF
. 2016.
Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.
Endosomes
Traber MG
,
Burton GW
,
Hamilton RL
. 2004.
Vitamin E trafficking.
.
Ann N Y Acad Sci. 1031:1-12.
Endoscopy
Nemanic S
,
Hollars K
,
Nelson NC
,
Bobe G
. 2015.
COMBINATION OF COMPUTED TOMOGRAPHIC IMAGING CHARACTERISTICS OF MEDIAL RETROPHARYNGEAL LYMPH NODES AND NASAL PASSAGES AIDS DISCRIMINATION BETWEEN RHINITIS AND NEOPLASIA IN CATS.
.
Vet Radiol Ultrasound. 56(6):617-27.
Endoplasmic Reticulum Stress
Joshi AD
,
Carter DE
,
Harper TA
,
Elferink CJ
. 2015.
Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress.
.
J Pharmacol Exp Ther. 353(1):201-12.
Tripathy S
,
Lytle KA
,
Stevens RD
,
Bain JR
,
Newgard CB
,
Greenberg AS
,
Huang L-S
,
Jump DB
. 2014.
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
.
J Lipid Res. 55(7):1448-64.
Endoplasmic Reticulum
Dixon BM
,
Heath S-HD
,
Kim R
,
Suh JH
,
Hagen TM
. 2008.
Assessment of endoplasmic reticulum glutathione redox status is confounded by extensive ex vivo oxidation.
.
Antioxid Redox Signal. 10(5):963-72.
Joshi AD
,
Carter DE
,
Harper TA
,
Elferink CJ
. 2015.
Aryl hydrocarbon receptor-dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against endoplasmic reticulum and oxidative stress.
.
J Pharmacol Exp Ther. 353(1):201-12.
Endopeptidases
Carr AC
. 2001.
Hypochlorous acid-modified low-density lipoprotein inactivates the lysosomal protease cathepsin B: protection by ascorbic and lipoic acids.
.
Redox Rep. 6(6):343-9.
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