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About the LPI
Faculty and Staff
Our Research
Micronutrient Information
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Biblio
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Inflammation
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Zandkarimi F
,
Vanegas J
,
Fern X
,
Maier CS
,
Bobe G
. 2018.
Metabotypes with elevated protein and lipid catabolism and inflammation precede clinical mastitis in prepartal transition dairy cows.
.
J Dairy Sci. 101(6):5531-5548.
Davis EW
,
Wong CP
,
Arnold HK
,
Kasschau K
,
Gaulke CA
,
Sharpton TJ
,
Ho E
. 2022.
Age and micronutrient effects on the microbiome in a mouse model of zinc depletion and supplementation.
.
PLoS One. 17(12):e0275352.
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Traber MG
. 2006.
Relationship of vitamin E metabolism and oxidation in exercising human subjects.
.
Br J Nutr. 96 Suppl 1:S34-7.
Traber MG
,
Mah E
,
Leonard SW
,
Bobe G
,
Bruno RS
. 2017.
Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.
.
Am J Clin Nutr. 105(3):571-579.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Riordan R
,
Rong W
,
Yu Z
,
Ross G
,
Valerio J
,
Dimas-Munoz J
,
Heredia V
,
Magnusson K
,
Galvan V
,
Perez VI
. 2023.
Effect of Nrf2 loss on senescence and cognition of tau-based P301S mice.
.
Geroscience. 45(3):1451-1469.
Zhang W-J
,
Frei B
. 2015.
Astragaloside IV inhibits NF- κ B activation and inflammatory gene expression in LPS-treated mice.
.
Mediators Inflamm. 2015:274314.
Matsumoto S
,
Traber MG
,
Leonard SW
,
Choi J
,
Fang X
,
Maishan M
,
Wick KD
,
Jones KD
,
Calfee CS
,
Gotts JE
et al.
. 2022.
Aerosolized vitamin E acetate causes oxidative injury in mice and in alveolar macrophages.
.
Am J Physiol Lung Cell Mol Physiol. 322(6):L771-L783.
Wong CP
,
Rinaldi NA
,
Ho E
. 2015.
Zinc deficiency enhanced inflammatory response by increasing immune cell activation and inducing IL6 promoter demethylation.
.
Mol Nutr Food Res. 59(5):991-9.
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Depner CM
,
Torres-Gonzalez M
,
Tripathy S
,
Milne G
,
Jump DB
. 2012.
Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.
.
J Nutr. 142(8):1495-503.
Newman NK
,
Zhang Y
,
Padiadpu J
,
Miranda CL
,
Magana AA
,
Wong CP
,
Hioki KA
,
Pederson JW
,
Li Z
,
Gurung M
et al.
. 2023.
Reducing gut microbiome-driven adipose tissue inflammation alleviates metabolic syndrome.
.
Microbiome. 11(1):208.
Zhang W-J
,
Wei H
,
Frei B
. 2010.
The iron chelator, desferrioxamine, reduces inflammation and atherosclerotic lesion development in experimental mice.
.
Exp Biol Med (Maywood). 235(5):633-41.
Shay KPetersen
,
Moreau RF
,
Smith EJ
,
Smith AR
,
Hagen TM
. 2009.
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.
.
Biochim Biophys Acta. 1790(10):1149-60.
Shay KPetersen
,
Moreau RF
,
Smith EJ
,
Hagen TM
. 2008.
Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity.
IUBMB Life. 60(6):362-7.
Li L
,
Smith A
,
Hagen TM
,
Frei B
. 2010.
Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.
.
Ann N Y Acad Sci. 1203:151-9.
Zhang W-J
,
Bird KE
,
McMillen TS
,
Leboeuf RC
,
Hagen TM
,
Frei B
. 2008.
Dietary alpha-lipoic acid supplementation inhibits atherosclerotic lesion development in apolipoprotein E-deficient and apolipoprotein E/low-density lipoprotein receptor-deficient mice.
.
Circulation. 117(3):421-8.
Inflammation Mediators
Mah E
,
Pei R
,
Guo Y
,
Ballard KD
,
Barker T
,
Rogers VE
,
Parker BA
,
Taylor AW
,
Traber MG
,
Volek JS
et al.
. 2013.
γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation.
.
Free Radic Biol Med. 65:1291-1299.
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Mah E
,
Sapper TN
,
Chitchumroonchokchai C
,
Failla ML
,
Schill KE
,
Clinton SK
,
Bobe G
,
Traber MG
,
Bruno RS
. 2015.
α-Tocopherol bioavailability is lower in adults with metabolic syndrome regardless of dairy fat co-ingestion: a randomized, double-blind, crossover trial.
.
Am J Clin Nutr. 102(5):1070-80.
Wei H
,
Zhang W-J
,
McMillen TS
,
Leboeuf RC
,
Frei B
. 2012.
Copper chelation by tetrathiomolybdate inhibits vascular inflammation and atherosclerotic lesion development in apolipoprotein E-deficient mice.
.
Atherosclerosis. 223(2):306-13.
Zhang W-J
,
Wei H
,
Tien Y-T
,
Frei B
. 2011.
Genetic ablation of phagocytic NADPH oxidase in mice limits TNFα-induced inflammation in the lungs but not other tissues.
.
Free Radic Biol Med. 50(11):1517-25.
Influenza, Human
Yoshino T
,
Arita R
,
Horiba Y
,
Watanabe K
. 2019.
The use of maoto (Ma-Huang-Tang), a traditional Japanese Kampo medicine, to alleviate flu symptoms: a systematic review and meta-analysis.
.
BMC Complement Altern Med. 19(1):68.
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