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Oxidative Stress
Mah E, Pei R, Guo Y, Ballard KD, Barker T, Rogers VE, Parker BA, Taylor AW, Traber MG, Volek JS et al..  2013.  γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation.. Free Radic Biol Med. 65:1291-1299.
McCall MR, Frei B.  1999.  Can antioxidant vitamins materially reduce oxidative damage in humans? Free Radic Biol Med. 26(7-8):1034-53.
Shay KPetersen, Hagen TM.  2009.  Age-associated impairment of Akt phosphorylation in primary rat hepatocytes is remediated by alpha-lipoic acid through PI3 kinase, PTEN, and PP2A.. Biogerontology. 10(4):443-56.
Hagen TM, Moreau R, Suh JH, Visioli F.  2002.  Mitochondrial decay in the aging rat heart: evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid.. Ann N Y Acad Sci. 959:491-507.
Ivanov V, Carr AC, Frei B.  2001.  Red wine antioxidants bind to human lipoproteins and protect them from metal ion-dependent and -independent oxidation.. J Agric Food Chem. 49(9):4442-9.
Pride H, Yu Z, Sunchu B, Mochnick J, Coles A, Zhang Y, Buffenstein R, Hornsby PJ, Austad SN, Perez VI.  2015.  Long-lived species have improved proteostasis compared to phylogenetically-related shorter-lived species.. Biochem Biophys Res Commun. 457(4):669-75.
Shay KPetersen, Moreau RF, Smith EJ, Hagen TM.  2008.  Is alpha-lipoic acid a scavenger of reactive oxygen species in vivo? Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity. IUBMB Life. 60(6):362-7.
Traber MG, Buettner GR, Bruno RS.  2019.  The relationship between vitamin C status, the gut-liver axis, and metabolic syndrome.. Redox Biol. 21:101091.
Traber MG.  2007.  Heart disease and single-vitamin supplementation.. Am J Clin Nutr. 85(1):293S-299S.
Suh JH, Shigeno ET, Morrow JD, Cox B, Rocha AE, Frei B, Hagen TM.  2001.  Oxidative stress in the aging rat heart is reversed by dietary supplementation with (R)-(alpha)-lipoic acid.. FASEB J. 15(3):700-6.
Song Y, Chung CS, Bruno RS, Traber MG, Brown KH, King JC, Ho E.  2009.  Dietary zinc restriction and repletion affects DNA integrity in healthy men.. Am J Clin Nutr. 90(2):321-8.
Forman HJay, Traber M, Ursini F.  2014.  Antioxidants: GRABbing new headlines.. Free Radic Biol Med. 66:1-2.
Taylor AW, Bruno RS, Traber MG.  2008.  Women and smokers have elevated urinary F(2)-isoprostane metabolites: a novel extraction and LC-MS methodology.. Lipids. 43(10):925-36.
Frei B, Birlouez-Aragon I, Lykkesfeldt J.  2012.  Authors' perspective: What is the optimum intake of vitamin C in humans? Crit Rev Food Sci Nutr. 52(9):815-29.
Bruno RS, Traber MG.  2005.  Cigarette smoke alters human vitamin E requirements.. J Nutr. 135(4):671-4.
Jump DB, Depner CM, Tripathy S, Lytle KA.  2015.  Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.. Adv Nutr. 6(6):694-702.
Li L, Smith A, Hagen TM, Frei B.  2010.  Vascular oxidative stress and inflammation increase with age: ameliorating effects of alpha-lipoic acid supplementation.. Ann N Y Acad Sci. 1203:151-9.
Li L, Frei B.  2006.  Iron chelation inhibits NF-kappaB-mediated adhesion molecule expression by inhibiting p22(phox) protein expression and NADPH oxidase activity.. Arterioscler Thromb Vasc Biol. 26(12):2638-43.
Kirkwood JS, Legette LCL, Miranda CL, Jiang Y, Stevens JF.  2013.  A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.. J Biol Chem. 288(26):19000-13.
Kuiper HC, Stevens JF.  2011.  LC-MS/MS quantitation of mercapturic acid conjugates of lipid peroxidation products as markers of oxidative stress.. Curr Protoc Toxicol. Chapter 17:Unit17.14.2.
Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN.  2002.  Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.. Proc Natl Acad Sci U S A. 99(4):1870-5.
McDougall M, Choi J, Truong L, Tanguay R, Traber MG.  2017.  Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets.. Free Radic Biol Med. 110:250-260.
Higdon JV, Frei B.  2003.  Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.. Crit Rev Food Sci Nutr. 43(1):89-143.
Depner CM, Traber MG, Bobe G, Kensicki E, Bohren KM, Milne G, Jump DB.  2013.  A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.. PLoS One. 8(12):e83756.
Li C, Zhang W-J, Choi J, Frei B.  2016.  Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase.. Redox Biol. 9:220-228.

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