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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Leonard, Scott W
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Cytochrome P-450 Enzyme System
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Mustacich DJ
,
Vo AT
,
Elias VD
,
Payne K
,
Sullivan L
,
Leonard SW
,
Traber MG
. 2007.
Regulatory mechanisms to control tissue alpha-tocopherol.
.
Free Radic Biol Med. 43(4):610-8.
Traber MG
,
Mustacich DJ
,
Sullivan LC
,
Leonard SW
,
Ahern-Rindell A
,
Kerkvliet N
. 2010.
Vitamin E status and metabolism in adult and aged aryl hydrocarbon receptor null mice.
.
J Nutr Biochem. 21(12):1193-9.
Mustacich DJ
,
Leonard SW
,
Devereaux MW
,
Sokol RJ
,
Traber MG
. 2006.
Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats.
.
Free Radic Biol Med. 41(7):1069-78.
Traber MG
,
Labut EM
,
Leonard SW
,
Lebold KM
. 2011.
α-Tocopherol injections in rats up-regulate hepatic ABC transporters, but not cytochrome P450 enzymes.
.
Free Radic Biol Med. 51(11):2031-40.
Cytochrome P450 Family 4
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Deuterium
Leonard SW
,
Terasawa Y
,
Farese RV
,
Traber MG
. 2002.
Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.
.
Am J Clin Nutr. 75(3):555-60.
Traber MG
,
Leonard SW
,
Ebenuwa I
,
Violet P-C
,
Wang Y
,
Niyyati M
,
Padayatty S
,
Tu H
,
Courville A
,
Bernstein S
et al.
. 2019.
Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.
.
Am J Clin Nutr. 110(5):1148-1167.
Traber MG
,
Leonard SW
,
Bobe G
,
Fu X
,
Saltzman E
,
Grusak MA
,
Booth SL
. 2015.
α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults.
.
Am J Clin Nutr. 101(4):752-9.
Leonard SW
,
Bruno RS
,
Ramakrishnan R
,
Bray T
,
Traber MG
. 2004.
Cigarette smoking increases human vitamin E requirements as estimated by plasma deuterium-labeled CEHC.
.
Ann N Y Acad Sci. 1031:357-60.
Farley SM
,
Leonard SW
,
Stevens JF
,
Traber MG
. 2014.
Deuterium-labeled phylloquinone fed to α-tocopherol-injected rats demonstrates sensitivity of low phylloquinone-containing tissues to menaquinone-4 depletion.
.
Mol Nutr Food Res. 58(8):1610-9.
Diet
Lim Y
,
Schock BC
,
Gohil K
,
Leonard SW
,
Packer L
,
Cross CE
,
Traber MG
. 2004.
Gene-nutrient interactions exemplified by the alpha-tocopherol content of tissues from alpha-tocopherol transfer protein-null mice fed different dietary vitamin E concentrations.
.
Ann N Y Acad Sci. 1031:328-9.
Bella DL
,
Schock BC
,
Lim Y
,
Leonard SW
,
Berry C
,
Cross CE
,
Traber MG
. 2006.
Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stress.
.
Lipids. 41(2):105-12.
Diet, High-Fat
Logan IE
,
Shulzhenko N
,
Sharpton TJ
,
Bobe G
,
Liu K
,
Nuss S
,
Jones ML
,
Miranda CL
,
Vasquez-Perez S
,
Pennington JM
et al.
. 2021.
Xanthohumol Requires the Intestinal Microbiota to Improve Glucose Metabolism in Diet-Induced Obese Mice.
.
Mol Nutr Food Res. 65(21):e2100389.
Dietary Fats
Traber MG
,
Leonard SW
,
Ebenuwa I
,
Violet P-C
,
Wang Y
,
Niyyati M
,
Padayatty S
,
Tu H
,
Courville A
,
Bernstein S
et al.
. 2019.
Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.
.
Am J Clin Nutr. 110(5):1148-1167.
Dietary Supplements
Farley SM
,
Leonard SW
,
Taylor AW
,
Birringer M
,
Edson KZ
,
Rettie AE
,
Traber MG
. 2013.
ω-Hydroxylation of phylloquinone by CYP4F2 is not increased by α-tocopherol.
.
Mol Nutr Food Res. 57(10):1785-93.
Pei R
,
Mah E
,
Leonard SW
,
Traber MG
,
Bruno RS
. 2015.
α-Tocopherol supplementation reduces 5-nitro-γ-tocopherol accumulation by decreasing γ-tocopherol in young adult smokers.
.
Free Radic Res. 49(9):1114-1121.
Tennant KG
,
Leonard SW
,
Wong CP
,
Iwaniec UT
,
Turner RT
,
Traber MG
. 2017.
High-Dietary Alpha-Tocopherol or Mixed Tocotrienols Have No Effect on Bone Mass, Density, or Turnover in Male Rats During Skeletal Maturation.
.
J Med Food. 20(7):700-708.
Bruno RS
,
Leonard SW
,
Atkinson J
,
Montine TJ
,
Ramakrishnan R
,
Bray TM
,
Traber MG
. 2006.
Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.
.
Free Radic Biol Med. 40(4):689-97.
Disease Models, Animal
Leonard SW
,
Terasawa Y
,
Farese RV
,
Traber MG
. 2002.
Incorporation of deuterated RRR- or all-rac-alpha-tocopherol in plasma and tissues of alpha-tocopherol transfer protein--null mice.
.
Am J Clin Nutr. 75(3):555-60.
Double-Blind Method
Bruno RS
,
Leonard SW
,
Atkinson J
,
Montine TJ
,
Ramakrishnan R
,
Bray TM
,
Traber MG
. 2006.
Faster plasma vitamin E disappearance in smokers is normalized by vitamin C supplementation.
.
Free Radic Biol Med. 40(4):689-97.
Bobe G
,
Cobb TJ
,
Leonard SW
,
Aponso S
,
Bahro CB
,
Koley D
,
Mah E
,
Bruno RS
,
Traber MG
. 2017.
Increased static and decreased capacity oxidation-reduction potentials in plasma are predictive of metabolic syndrome.
.
Redox Biol. 12:121-128.
Traber MG
,
Mah E
,
Leonard SW
,
Bobe G
,
Bruno RS
. 2017.
Metabolic syndrome increases dietary α-tocopherol requirements as assessed using urinary and plasma vitamin E catabolites: a double-blind, crossover clinical trial.
.
Am J Clin Nutr. 105(3):571-579.
Eating
Bella DL
,
Schock BC
,
Lim Y
,
Leonard SW
,
Berry C
,
Cross CE
,
Traber MG
. 2006.
Regulation of the alpha-tocopherol transfer protein in mice: lack of response to dietary vitamin E or oxidative stress.
.
Lipids. 41(2):105-12.
Edible Grain
Leonard SW
,
Good CK
,
Gugger ET
,
Traber MG
. 2004.
Vitamin E bioavailability from fortified breakfast cereal is greater than that from encapsulated supplements.
.
Am J Clin Nutr. 79(1):86-92.
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