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Faculty and Staff
Our Research
Micronutrient Information
Publications
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Biblio
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Dashwood, Wan-Mohaiza
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Male
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Mice
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Mice, Inbred BALB C
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
Mice, Inbred C57BL
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Mice, Mutant Strains
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Mice, Nude
Myzak MC
,
Tong P
,
Dashwood W-M
,
Dashwood RH
,
Ho E
. 2007.
Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.
.
Exp Biol Med (Maywood). 232(2):227-34.
MicroRNAs
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
Middle Aged
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Molecular Sequence Data
Li Q
,
Dashwood W-M
,
Zhong X
,
Al-Fageeh M
,
Dashwood RH
. 2004.
Cloning of the rat beta-catenin gene (Ctnnb1) promoter and its functional analysis compared with the Catnb and CTNNB1 promoters.
.
Genomics. 83(2):231-42.
Mutation
Orner GA
,
Dashwood W-M
,
Dashwood RH
. 2004.
Tumor-suppressing effects of antioxidants from tea.
.
J Nutr. 134(11):3177S-3178S.
NADPH Oxidases
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Neoplasm Invasiveness
Wang R
,
Chen Y-S
,
Dashwood W-M
,
Li Q
,
Löhr CV
,
Fischer K
,
Ho E
,
Williams DE
,
Dashwood RH
. 2017.
Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.
.
Mol Carcinog. 56(7):1733-1742.
Neoplasms
Chen Y-S
,
Wang R
,
Dashwood W-M
,
Löhr CV
,
Williams DE
,
Ho E
,
Mertens-Talcott S
,
Dashwood RH
. 2017.
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat.
.
Arch Toxicol. 91(10):3415-3425.
NF-kappa B p50 Subunit
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Nuclear Proteins
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Phosphorylation
Wang R
,
Dashwood W-M
,
Nian H
,
Löhr CV
,
Fischer KA
,
Tsuchiya N
,
Nakagama H
,
Ashktorab H
,
Dashwood RH
. 2011.
NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Int J Cancer. 128(11):2581-90.
Plant Extracts
Orner GA
,
Dashwood W-M
,
Blum CA
,
G Díaz D
,
Li Q
,
Al-Fageeh M
,
Tebbutt N
,
Heath JK
,
Ernst M
,
Dashwood RH
. 2002.
Response of Apc(min) and A33 (delta N beta-cat) mutant mice to treatment with tea, sulindac, and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP).
.
Mutat Res. 506-507:121-7.
Polymorphism, Single Nucleotide
Blum CA
,
Tanaka T
,
Zhong X
,
Li Q
,
Dashwood W-M
,
Pereira C
,
Xu M
,
Dashwood RH
. 2003.
Mutational analysis of Ctnnb1 and Apc in tumors from rats given 1,2-dimethylhydrazine or 2-amino-3-methylimidazo[4,5-f]quinoline: mutational 'hotspots' and the relative expression of beta-catenin and c-jun.
.
Mol Carcinog. 36(4):195-203.
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