Found 189 results
Author [ Keyword(Desc)] Title Type Year
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Enzyme Inhibitors
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Zhu B-Z, Carr AC, Frei B.  2002.  Pyrrolidine dithiocarbamate is a potent antioxidant against hypochlorous acid-induced protein damage.. FEBS Lett. 532(1-2):80-4.
Myzak MC, P Karplus A, Chung F-L, Dashwood RH.  2004.  A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.. Cancer Res. 64(16):5767-74.
Dashwood RH.  2006.  Xenobiotic metabolism relevance to cancer.. J Nutr. 136(10):2681S-2S.
Enzyme Repression
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Enzyme Stability
Krueger SK, Henderson MC, Siddens LK, VanDyke JE, Benninghoff AD, P Karplus A, Furnes B, Schlenk D, Williams DE.  2009.  Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.. Drug Metab Dispos. 37(8):1785-91.
Krueger SK, Martin SR, Yueh M-F, Pereira CB, Williams DE.  2002.  Identification of active flavin-containing monooxygenase isoform 2 in human lung and characterization of expressed protein.. Drug Metab Dispos. 30(1):34-41.
Enzyme-Linked Immunosorbent Assay
Zhang W-J, Frei B.  2002.  Albumin selectively inhibits TNF alpha-induced expression of vascular cell adhesion molecule-1 in human aortic endothelial cells.. Cardiovasc Res. 55(4):820-9.
Taylor AW, Bruno RS, Frei B, Traber MG.  2006.  Benefits of prolonged gradient separation for high-performance liquid chromatography-tandem mass spectrometry quantitation of plasma total 15-series F-isoprostanes.. Anal Biochem. 350(1):41-51.
Epidermis
Bhattacharya N, Sato WJ, Kelly A, Ganguli-Indra G, Indra AK.  2019.  Epidermal Lipids: Key Mediators of Atopic Dermatitis Pathogenesis.. Trends Mol Med. 25(6):551-562.
Epigenesis, Genetic
Abbas A, J Hall A, Patterson WL, Ho E, Hsu A, Al-Mulla F, Georgel PT.  2016.  Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.. Biochem Cell Biol. 94(1):71-81.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Dashwood RH.  2007.  Frontiers in polyphenols and cancer prevention.. J Nutr. 137(1 Suppl):267S-269S.
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Johnson LA, Torres ERuth S, Impey S, Stevens JF, Raber J.  2017.  Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.. Sci Rep. 7:43701.
Ho E, Beaver LM, Williams DE, Dashwood RH.  2011.  Dietary factors and epigenetic regulation for prostate cancer prevention.. Adv Nutr. 2(6):497-510.
Delage B, Dashwood RH.  2008.  Dietary manipulation of histone structure and function.. Annu Rev Nutr. 28:347-66.
Parasramka MA, Ho E, Williams DE, Dashwood RH.  2012.  MicroRNAs, diet, and cancer: new mechanistic insights on the epigenetic actions of phytochemicals.. Mol Carcinog. 51(3):213-30.
Epigenetic Repression
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Epigenomics
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Epithelial Cells
Campbell Y, Fantacone ML, Gombart AF.  2012.  Regulation of antimicrobial peptide gene expression by nutrients and by-products of microbial metabolism.. Eur J Nutr. 51(8):899-907.
Dhawan P, Wei R, Sun C, Gombart AF, H Koeffler P, Diamond G, Christakos S.  2015.  C/EBPα and the Vitamin D Receptor Cooperate in the Regulation of Cathelicidin in Lung Epithelial Cells.. J Cell Physiol. 230(2):464-72.
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.

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