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Faculty and Staff
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Found 610 results
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Williams, David E
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Child
Williams DE
. 2018.
Association Is Not Causation.
.
Toxicol Sci. 164(1):3.
Chlorophyll
Simonich MT
,
McQuistan T
,
Jubert C
,
Pereira C
,
Hendricks JD
,
Schimerlik M
,
Zhu B
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2008.
Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.
.
Food Chem Toxicol. 46(3):1014-24.
McQuistan TJ
,
Simonich MT
,
M Pratt M
,
Pereira CB
,
Hendricks JD
,
Dashwood RH
,
Williams DE
,
Bailey GS
. 2012.
Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.
.
Food Chem Toxicol. 50(2):341-52.
Simonich MT
,
Egner PA
,
Roebuck BD
,
Orner GA
,
Jubert C
,
Pereira C
,
Groopman JD
,
Kensler TW
,
Dashwood RH
,
Williams DE
et al.
. 2007.
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
.
Carcinogenesis. 28(6):1294-302.
Chlorophyllides
Williams DE
. 2012.
The rainbow trout liver cancer model: response to environmental chemicals and studies on promotion and chemoprevention.
.
Comp Biochem Physiol C Toxicol Pharmacol. 155(1):121-7.
Chimploy K
,
G Díaz D
,
Li Q
,
Carter O
,
Dashwood W-M
,
Mathews CK
,
Williams DE
,
Bailey GS
,
Dashwood RH
. 2009.
E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.
.
Int J Cancer. 125(9):2086-94.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Cholates
Krueger SK
,
Henderson MC
,
Siddens LK
,
VanDyke JE
,
Benninghoff AD
,
P Karplus A
,
Furnes B
,
Schlenk D
,
Williams DE
. 2009.
Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.
.
Drug Metab Dispos. 37(8):1785-91.
Chromans
Traber MG
,
Siddens LK
,
Leonard SW
,
Schock B
,
Gohil K
,
Krueger SK
,
Cross CE
,
Williams DE
. 2005.
Alpha-tocopherol modulates Cyp3a expression, increases gamma-CEHC production, and limits tissue gamma-tocopherol accumulation in mice fed high gamma-tocopherol diets.
.
Free Radic Biol Med. 38(6):773-85.
Chromatin
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Chromatin Assembly and Disassembly
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2011.
Metabolism as a key to histone deacetylase inhibition.
.
Crit Rev Biochem Mol Biol. 46(3):181-99.
Chromatin Immunoprecipitation
Wong CP
,
Hsu A
,
Buchanan A
,
Palomera-Sanchez Z
,
Beaver LM
,
E Houseman A
,
Williams DE
,
Dashwood RH
,
Ho E
. 2014.
Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.
.
PLoS One. 9(1):e86787.
Palomera-Sanchez Z
,
Watson GW
,
Wong CP
,
Beaver LM
,
Williams DE
,
Dashwood RH
,
Ho E
. 2017.
The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.
.
J Nutr Biochem. 47:113-119.
Chromatography, High Pressure Liquid
Henderson MC
,
Krueger SK
,
Stevens JF
,
Williams DE
. 2004.
Human flavin-containing monooxygenase form 2 S-oxygenation: sulfenic acid formation from thioureas and oxidation of glutathione.
.
Chem Res Toxicol. 17(5):633-40.
Harper TA
,
Morré J
,
Lauer FT
,
McQuistan TJ
,
Hummel JM
,
Burchiel SW
,
Williams DE
. 2015.
Analysis of dibenzo[def,p]chrysene-deoxyadenosine adducts in wild-type and cytochrome P450 1b1 knockout mice using stable-isotope dilution UHPLC-MS/MS.
.
Mutat Res Genet Toxicol Environ Mutagen. 782:51-6.
Chromatography, Liquid
Bouranis JA
,
Beaver LM
,
Jiang D
,
Choi J
,
Wong CP
,
Davis EW
,
Williams DE
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2022.
Interplay between Cruciferous Vegetables and the Gut Microbiome: A Multi-Omic Approach.
.
Nutrients. 15(1)
Chrysenes
Madeen EP
,
Löhr CV
,
You H
,
Siddens LK
,
Krueger SK
,
Dashwood RH
,
Gonzalez FJ
,
Baird WM
,
Ho E
,
Bramer L
et al.
. 2017.
Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.
.
Mol Carcinog. 56(1):163-171.
Coal Tar
Siddens LK
,
Bunde KL
,
Harper TA
,
McQuistan TJ
,
Löhr CV
,
Bramer LM
,
Waters KM
,
Tilton SC
,
Krueger SK
,
Williams DE
et al.
. 2015.
Cytochrome P450 1b1 in polycyclic aromatic hydrocarbon (PAH)-induced skin carcinogenesis: Tumorigenicity of individual PAHs and coal-tar extract, DNA adduction and expression of select genes in the Cyp1b1 knockout mouse.
.
Toxicol Appl Pharmacol. 287(2):149-160.
Colon
Johnson GS
,
Li J
,
Beaver LM
,
W Dashwood M
,
Sun D
,
Rajendran P
,
Williams DE
,
Ho E
,
Dashwood RH
. 2017.
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.
.
Mol Nutr Food Res. 61(4)
Rajendran P
,
Kidane AI
,
Yu T-W
,
Dashwood W-M
,
Bisson WH
,
Löhr CV
,
Ho E
,
Williams DE
,
Dashwood RH
. 2013.
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.
.
Epigenetics. 8(6):612-23.
Wang R
,
W Dashwood M
,
Löhr CV
,
Fischer KA
,
Nakagama H
,
Williams DE
,
Dashwood RH
. 2008.
beta-catenin is strongly elevated in rat colonic epithelium following short-term intermittent treatment with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and a high-fat diet.
.
Cancer Sci. 99(9):1754-9.
Colonic Neoplasms
Simonich MT
,
Egner PA
,
Roebuck BD
,
Orner GA
,
Jubert C
,
Pereira C
,
Groopman JD
,
Kensler TW
,
Dashwood RH
,
Williams DE
et al.
. 2007.
Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.
.
Carcinogenesis. 28(6):1294-302.
Wang R
,
W Dashwood M
,
Bailey GS
,
Williams DE
,
Dashwood RH
. 2006.
Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.
.
Mutat Res. 601(1-2):11-8.
Parasramka MA
,
W Dashwood M
,
Wang R
,
Abdelli A
,
Bailey GS
,
Williams DE
,
Ho E
,
Dashwood RH
. 2012.
MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.
.
Mol Nutr Food Res. 56(8):1259-69.
Wang R
,
Kang Y
,
Löhr CV
,
Fischer KA
,
C Bradford S
,
Johnson G
,
Dashwood WMohaiza
,
Williams DE
,
Ho E
,
Dashwood RH
. 2016.
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.
.
Cancer Lett. 381(2):341-8.
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