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Found 324 results
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Beckman, Joseph S
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Mice, Transgenic
Kim MJin
,
Vargas MR
,
Harlan BA
,
Killoy KM
,
Ball LE
,
Comte-Walters S
,
Gooz M
,
Yamamoto Y
,
Beckman JS
,
Barbeito L
et al.
. 2018.
Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.
.
Antioxid Redox Signal. 28(18):1587-1602.
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Ermilova IP
,
Ermilov VB
,
Levy M
,
Ho E
,
Pereira C
,
Beckman JS
. 2005.
Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.
.
Neurosci Lett. 379(1):42-6.
Microglia
Liddell JR
,
Hilton JBW
,
Kysenius K
,
Billings JL
,
Nikseresht S
,
McInnes LE
,
Hare DJ
,
Paul B
,
Mercer SW
,
Belaidi AA
et al.
. 2024.
Microglial ferroptotic stress causes non-cell autonomous neuronal death.
.
Mol Neurodegener. 19(1):14.
Kovacs M
,
Trias E
,
Varela V
,
Ibarburu S
,
Beckman JS
,
Moura IC
,
Hermine O
,
King PH
,
Si Y
,
Kwon Y
et al.
. 2019.
CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.
.
Int J Mol Sci. 20(16)
Microscopy, Confocal
Robinson KM
,
Janes MS
,
Pehar M
,
Monette JS
,
Ross MF
,
Hagen TM
,
Murphy MP
,
Beckman JS
. 2006.
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.
.
Proc Natl Acad Sci U S A. 103(41):15038-43.
Microscopy, Fluorescence
Robinson KM
,
Janes MS
,
Beckman JS
. 2008.
The selective detection of mitochondrial superoxide by live cell imaging.
.
Nat Protoc. 3(6):941-7.
Mitochondria
Beckman JS
,
Esétvez AG
,
Barbeito L
,
Crow JP
. 2002.
CCS knockout mice establish an alternative source of copper for SOD in ALS.
.
Free Radic Biol Med. 33(10):1433-5.
Robinson KM
,
Janes MS
,
Pehar M
,
Monette JS
,
Ross MF
,
Hagen TM
,
Murphy MP
,
Beckman JS
. 2006.
Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.
.
Proc Natl Acad Sci U S A. 103(41):15038-43.
Robinson KM
,
Janes MS
,
Beckman JS
. 2008.
The selective detection of mitochondrial superoxide by live cell imaging.
.
Nat Protoc. 3(6):941-7.
Schwarzländer M
,
Wagner S
,
Ermakova YG
,
Belousov VV
,
Radi R
,
Beckman JS
,
Buettner GR
,
Demaurex N
,
Duchen MR
,
Forman HJ
et al.
. 2014.
The 'mitoflash' probe cpYFP does not respond to superoxide.
.
Nature. 514(7523):E12-4.
Visioli F
,
Ingram A
,
Beckman JS
,
Magnusson KR
,
Hagen TM
. 2022.
Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?
Free Radic Biol Med. 178:330-346.
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Mitophagy
Visioli F
,
Ingram A
,
Beckman JS
,
Magnusson KR
,
Hagen TM
. 2022.
Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help?
Free Radic Biol Med. 178:330-346.
Models, Molecular
Trumbull KA
,
Beckman JS
. 2009.
A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.
.
Antioxid Redox Signal. 11(7):1627-39.
Voinov VG
,
Hoffman PD
,
Bennett SE
,
Beckman JS
,
Barofsky DF
. 2015.
Electron Capture Dissociation of Sodium-Adducted Peptides on a Modified Quadrupole/Time-of-Flight Mass Spectrometer.
.
J Am Soc Mass Spectrom. 26(12):2096-104.
Molecular Chaperones
Williams JR
,
Trias E
,
Beilby PR
,
Lopez NI
,
Labut EM
,
C Bradford S
,
Roberts BR
,
McAllum EJ
,
Crouch PJ
,
Rhoads TW
et al.
. 2016.
Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
.
Neurobiol Dis. 89:1-9.
Beckman JS
,
Esétvez AG
,
Barbeito L
,
Crow JP
. 2002.
CCS knockout mice establish an alternative source of copper for SOD in ALS.
.
Free Radic Biol Med. 33(10):1433-5.
Molybdenum
Wei H
,
Frei B
,
Beckman JS
,
Zhang W-J
. 2011.
Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.
.
Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Motor Neurons
Kim MJin
,
Vargas MR
,
Harlan BA
,
Killoy KM
,
Ball LE
,
Comte-Walters S
,
Gooz M
,
Yamamoto Y
,
Beckman JS
,
Barbeito L
et al.
. 2018.
Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.
.
Antioxid Redox Signal. 28(18):1587-1602.
Trias E
,
Ibarburu S
,
Barreto-Núñez R
,
Babdor J
,
Maciel TT
,
Guillo M
,
Gros L
,
Dubreuil P
,
Díaz-Amarilla P
,
Cassina P
et al.
. 2016.
Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.
.
J Neuroinflammation. 13(1):177.
Trumbull KA
,
McAllister D
,
Gandelman MM
,
Fung WY
,
Lew T
,
Brennan L
,
Lopez N
,
Morré J
,
Kalyanaraman B
,
Beckman JS
. 2012.
Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.
.
Neurobiol Dis. 45(1):137-44.
Hilton JB
,
Mercer SW
,
Lim NKH
,
Faux NG
,
Buncic G
,
Beckman JS
,
Roberts BR
,
Donnelly PS
,
White AR
,
Crouch PJ
. 2017.
Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.
.
Sci Rep. 7:42292.
Kovacs M
,
Trias E
,
Varela V
,
Ibarburu S
,
Beckman JS
,
Moura IC
,
Hermine O
,
King PH
,
Si Y
,
Kwon Y
et al.
. 2019.
CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.
.
Int J Mol Sci. 20(16)
Trumbull KA
,
Beckman JS
. 2009.
A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.
.
Antioxid Redox Signal. 11(7):1627-39.
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