Found 324 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Beckman, Joseph S  [Clear All Filters]
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Mice, Transgenic
Ermilova IP, Ermilov VB, Levy M, Ho E, Pereira C, Beckman JS.  2005.  Protection by dietary zinc in ALS mutant G93A SOD transgenic mice.. Neurosci Lett. 379(1):42-6.
Hilton JBW, Kysenius K, Liddell JR, Mercer SW, Paul B, Beckman JS, McLean CA, White AR, Donnelly PS, Bush AI et al..  2024.  Evidence for disrupted copper availability in human spinal cord supports Cu(atsm) as a treatment option for sporadic cases of ALS.. Sci Rep. 14(1):5929.
Trumbull KA, Beckman JS.  2009.  A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.. Antioxid Redox Signal. 11(7):1627-39.
Microglia
Liddell JR, Hilton JBW, Kysenius K, Billings JL, Nikseresht S, McInnes LE, Hare DJ, Paul B, Mercer SW, Belaidi AA et al..  2024.  Microglial ferroptotic stress causes non-cell autonomous neuronal death.. Mol Neurodegener. 19(1):14.
Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)
Microscopy, Confocal
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Microscopy, Fluorescence
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Mitochondria
Visioli F, Ingram A, Beckman JS, Magnusson KR, Hagen TM.  2022.  Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help? Free Radic Biol Med. 178:330-346.
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Beckman JS, Esétvez AG, Barbeito L, Crow JP.  2002.  CCS knockout mice establish an alternative source of copper for SOD in ALS.. Free Radic Biol Med. 33(10):1433-5.
Robinson KM, Janes MS, Pehar M, Monette JS, Ross MF, Hagen TM, Murphy MP, Beckman JS.  2006.  Selective fluorescent imaging of superoxide in vivo using ethidium-based probes.. Proc Natl Acad Sci U S A. 103(41):15038-43.
Robinson KM, Janes MS, Beckman JS.  2008.  The selective detection of mitochondrial superoxide by live cell imaging.. Nat Protoc. 3(6):941-7.
Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ et al..  2014.  The 'mitoflash' probe cpYFP does not respond to superoxide.. Nature. 514(7523):E12-4.
Mitophagy
Visioli F, Ingram A, Beckman JS, Magnusson KR, Hagen TM.  2022.  Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help? Free Radic Biol Med. 178:330-346.
Models, Molecular
Voinov VG, Hoffman PD, Bennett SE, Beckman JS, Barofsky DF.  2015.  Electron Capture Dissociation of Sodium-Adducted Peptides on a Modified Quadrupole/Time-of-Flight Mass Spectrometer.. J Am Soc Mass Spectrom. 26(12):2096-104.
Trumbull KA, Beckman JS.  2009.  A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.. Antioxid Redox Signal. 11(7):1627-39.
Molecular Chaperones
Beckman JS, Esétvez AG, Barbeito L, Crow JP.  2002.  CCS knockout mice establish an alternative source of copper for SOD in ALS.. Free Radic Biol Med. 33(10):1433-5.
Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, C Bradford S, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW et al..  2016.  Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.. Neurobiol Dis. 89:1-9.
Molybdenum
Wei H, Frei B, Beckman JS, Zhang W-J.  2011.  Copper chelation by tetrathiomolybdate inhibits lipopolysaccharide-induced inflammatory responses in vivo.. Am J Physiol Heart Circ Physiol. 301(3):H712-20.
Motor Neurons
Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P et al..  2016.  Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis.. J Neuroinflammation. 13(1):177.
Trumbull KA, McAllister D, Gandelman MM, Fung WY, Lew T, Brennan L, Lopez N, Morré J, Kalyanaraman B, Beckman JS.  2012.  Diapocynin and apocynin administration fails to significantly extend survival in G93A SOD1 ALS mice.. Neurobiol Dis. 45(1):137-44.
Hilton JB, Mercer SW, Lim NKH, Faux NG, Buncic G, Beckman JS, Roberts BR, Donnelly PS, White AR, Crouch PJ.  2017.  Cu(atsm) improves the neurological phenotype and survival of SOD1 mice and selectively increases enzymatically active SOD1 in the spinal cord.. Sci Rep. 7:42292.
Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y et al..  2019.  CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS.. Int J Mol Sci. 20(16)
Trumbull KA, Beckman JS.  2009.  A role for copper in the toxicity of zinc-deficient superoxide dismutase to motor neurons in amyotrophic lateral sclerosis.. Antioxid Redox Signal. 11(7):1627-39.
Kim MJin, Vargas MR, Harlan BA, Killoy KM, Ball LE, Comte-Walters S, Gooz M, Yamamoto Y, Beckman JS, Barbeito L et al..  2018.  Nitration and Glycation Turn Mature NGF into a Toxic Factor for Motor Neurons: A Role for p75 and RAGE Signaling in ALS.. Antioxid Redox Signal. 28(18):1587-1602.

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