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Faculty and Staff
Our Research
Micronutrient Information
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Stevens, Jan F
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Disease Models, Animal
Kirkwood JS
,
Legette LCL
,
Miranda CL
,
Jiang Y
,
Stevens JF
. 2013.
A metabolomics-driven elucidation of the anti-obesity mechanisms of xanthohumol.
.
J Biol Chem. 288(26):19000-13.
Khorani M
,
Bobe G
,
Matthews DG
,
Magana AAlcazar
,
Caruso M
,
Gray NE
,
Quinn JF
,
Stevens JF
,
Soumyanath A
,
Maier CS
. 2022.
The Impact of the hAPP695SW Transgene and Associated Amyloid-β Accumulation on Murine Hippocampal Biochemical Pathways.
.
J Alzheimers Dis. 85(4):1601-1619.
Johnson LA
,
Zuloaga KL
,
Kugelman TL
,
Mader KS
,
Morré JT
,
Zuloaga DG
,
Weber S
,
Marzulla T
,
Mulford A
,
Button D
et al.
. 2016.
Amelioration of Metabolic Syndrome-Associated Cognitive Impairments in Mice via a Reduction in Dietary Fat Content or Infusion of Non-Diabetic Plasma.
.
EBioMedicine. 3:26-42.
Disease Susceptibility
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
DNA Methylation
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
Docosahexaenoic Acids
McDougall MQ
,
Choi J
,
Stevens JF
,
Truong L
,
Tanguay RL
,
Traber MG
. 2016.
Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos.
.
Redox Biol. 8:165-74.
Dose-Response Relationship, Drug
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Legette LC
,
Karnpracha C
,
Reed RL
,
Choi J
,
Bobe G
,
J Christensen M
,
Rodriguez-Proteau R
,
Purnell JQ
,
Stevens JF
. 2014.
Human pharmacokinetics of xanthohumol, an antihyperglycemic flavonoid from hops.
.
Mol Nutr Food Res. 58(2):248-55.
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
Gray NE
,
Morré J
,
Kelley J
,
Maier CS
,
Stevens JF
,
Quinn JF
,
Soumyanath A
. 2014.
Caffeoylquinic acids in Centella asiatica protect against amyloid-β toxicity.
.
J Alzheimers Dis. 40(2):359-73.
Double-Blind Method
Kuiper HC
,
Bruno RS
,
Traber MG
,
Stevens JF
. 2011.
Vitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humans.
.
Free Radic Biol Med. 50(7):848-53.
Drosophila melanogaster
Holvoet H
,
Long DM
,
Law A
,
McClure C
,
Choi J
,
Yang L
,
Marney L
,
Poeck B
,
Strauss R
,
Stevens JF
et al.
. 2022.
Extracts Promote Resilience against Age-Related and Stress-Induced Behavioral Phenotypes in a Possible Role of Other Compounds besides Withanolides.
.
Nutrients. 14(19)
Drug Compounding
DenHerder JM
,
Reed RL
,
Sargent JL
,
Bobe G
,
Stevens JF
,
Diggs HE
. 2017.
Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Buprenorphine for Injection.
.
J Am Assoc Lab Anim Sci. 56(4):457-461.
Drug Stability
DenHerder JM
,
Reed RL
,
Sargent JL
,
Bobe G
,
Stevens JF
,
Diggs HE
. 2017.
Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Buprenorphine for Injection.
.
J Am Assoc Lab Anim Sci. 56(4):457-461.
Drug Storage
DenHerder JM
,
Reed RL
,
Sargent JL
,
Bobe G
,
Stevens JF
,
Diggs HE
. 2017.
Effects of Time and Storage Conditions on the Chemical and Microbiologic Stability of Diluted Buprenorphine for Injection.
.
J Am Assoc Lab Anim Sci. 56(4):457-461.
Dyslipidemias
Legette LC
,
Ma L
,
Reed RL
,
Miranda CL
,
Christensen JMark
,
Rodriguez-Proteau R
,
Stevens JF
. 2012.
Pharmacokinetics of xanthohumol and metabolites in rats after oral and intravenous administration.
.
Mol Nutr Food Res. 56(3):466-74.
Eating
Legette LCL
,
Luna AYMoreno
,
Reed RL
,
Miranda CL
,
Bobe G
,
Proteau RR
,
Stevens JF
. 2013.
Xanthohumol lowers body weight and fasting plasma glucose in obese male Zucker fa/fa rats.
.
Phytochemistry. 91:236-41.
Electrons
Sowell J
,
Frei B
,
Stevens JF
. 2004.
Vitamin C conjugates of genotoxic lipid peroxidation products: structural characterization and detection in human plasma.
.
Proc Natl Acad Sci U S A. 101(52):17964-9.
Embryo, Nonmammalian
McDougall MQ
,
Choi J
,
Stevens JF
,
Truong L
,
Tanguay RL
,
Traber MG
. 2016.
Lipidomics and H2(18)O labeling techniques reveal increased remodeling of DHA-containing membrane phospholipids associated with abnormal locomotor responses in α-tocopherol deficient zebrafish (danio rerio) embryos.
.
Redox Biol. 8:165-74.
Endothelial Cells
Axton ER
,
Hardardt EA
,
Stevens JF
. 2016.
Stable isotope-assisted LC-MS/MS monitoring of glyceryl trinitrate bioactivation in a cell culture model of nitrate tolerance.
.
J Chromatogr B Analyt Technol Biomed Life Sci. 1019:156-63.
Energy Metabolism
Kirkwood JS
,
Lebold KM
,
Miranda CL
,
Wright CL
,
Miller GW
,
Tanguay RL
,
Barton CL
,
Traber MG
,
Stevens JF
. 2012.
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish.
.
J Biol Chem. 287(6):3833-41.
Traber MG
,
Stevens JF
. 2011.
Vitamins C and E: beneficial effects from a mechanistic perspective.
.
Free Radic Biol Med. 51(5):1000-13.
Enterobacteriaceae
Bouranis JA
,
Beaver LM
,
Choi J
,
Wong CP
,
Jiang D
,
Sharpton TJ
,
Stevens JF
,
Ho E
. 2021.
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts.
.
Nutrients. 13(9)
Enzyme Inhibitors
Kubglomsong S
,
Theerakulkait C
,
Reed RL
,
Yang L
,
Maier CS
,
Stevens JF
. 2018.
Isolation and Identification of Tyrosinase-Inhibitory and Copper-Chelating Peptides from Hydrolyzed Rice-Bran-Derived Albumin.
.
J Agric Food Chem. 66(31):8346-8354.
Epigenesis, Genetic
Johnson LA
,
Torres ERuth S
,
Impey S
,
Stevens JF
,
Raber J
. 2017.
Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome.
.
Sci Rep. 7:43701.
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