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Non-alcoholic Fatty Liver Disease
Lytle KA
,
Wong CP
,
Jump DB
. 2017.
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
.
PLoS One. 12(4):e0173376.
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
Jump DB
,
Tripathy S
,
Depner CM
. 2013.
Fatty acid-regulated transcription factors in the liver.
.
Annu Rev Nutr. 33:249-69.
Lytle KA
,
Depner CM
,
Wong CP
,
Jump DB
. 2015.
Docosahexaenoic acid attenuates Western diet-induced hepatic fibrosis in Ldlr-/- mice by targeting the TGFβ-Smad3 pathway.
.
J Lipid Res. 56(10):1936-46.
Jump DB
,
Depner CM
,
Tripathy S
,
Lytle KA
. 2015.
Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.
.
Adv Nutr. 6(6):694-702.
Obesity
Tripathy S
,
Lytle KA
,
Stevens RD
,
Bain JR
,
Newgard CB
,
Greenberg AS
,
Huang L-S
,
Jump DB
. 2014.
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
.
J Lipid Res. 55(7):1448-64.
Jump DB
,
Depner CM
,
Tripathy S
,
Lytle KA
. 2015.
Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.
.
Adv Nutr. 6(6):694-702.
Olive Oil
Lytle KA
,
Wong CP
,
Jump DB
. 2017.
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
.
PLoS One. 12(4):e0173376.
Osteopontin
Lytle KA
,
Wong CP
,
Jump DB
. 2017.
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
.
PLoS One. 12(4):e0173376.
Oxidation-Reduction
Jump DB
,
Torres-Gonzalez M
,
L Olson K
. 2011.
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.
.
Biochem Pharmacol. 81(5):649-60.
Oxidative Stress
Jump DB
,
Tripathy S
,
Depner CM
. 2013.
Fatty acid-regulated transcription factors in the liver.
.
Annu Rev Nutr. 33:249-69.
Depner CM
,
Torres-Gonzalez M
,
Tripathy S
,
Milne G
,
Jump DB
. 2012.
Menhaden oil decreases high-fat diet-induced markers of hepatic damage, steatosis, inflammation, and fibrosis in obese Ldlr-/- mice.
.
J Nutr. 142(8):1495-503.
Jump DB
,
Depner CM
,
Tripathy S
,
Lytle KA
. 2015.
Potential for dietary ω-3 fatty acids to prevent nonalcoholic fatty liver disease and reduce the risk of primary liver cancer.
.
Adv Nutr. 6(6):694-702.
Lytle KA
,
Jump DB
. 2016.
Is Western Diet-Induced Nonalcoholic Steatohepatitis in Ldlr-/- Mice Reversible?
PLoS One. 11(1):e0146942.
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
Palmitic Acid
Jump DB
,
Torres-Gonzalez M
,
L Olson K
. 2011.
Soraphen A, an inhibitor of acetyl CoA carboxylase activity, interferes with fatty acid elongation.
.
Biochem Pharmacol. 81(5):649-60.
Phospholipids
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
PPAR alpha
Jump DB
. 2008.
N-3 polyunsaturated fatty acid regulation of hepatic gene transcription.
.
Curr Opin Lipidol. 19(3):242-7.
PPAR-beta
Tripathy S
,
Lytle KA
,
Stevens RD
,
Bain JR
,
Newgard CB
,
Greenberg AS
,
Huang L-S
,
Jump DB
. 2014.
Fatty acid elongase-5 (Elovl5) regulates hepatic triglyceride catabolism in obese C57BL/6J mice.
.
J Lipid Res. 55(7):1448-64.
Protein-Lysine 6-Oxidase
Lytle KA
,
Wong CP
,
Jump DB
. 2017.
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
.
PLoS One. 12(4):e0173376.
Rats
Jump DB
. 2009.
Mammalian fatty acid elongases.
.
Methods Mol Biol. 579:375-89.
Rats, Sprague-Dawley
Jump DB
. 2009.
Mammalian fatty acid elongases.
.
Methods Mol Biol. 579:375-89.
Real-Time Polymerase Chain Reaction
Lebold KM
,
Jump DB
,
Miller GW
,
Wright CL
,
Labut EM
,
Barton CL
,
Tanguay RL
,
Traber MG
. 2011.
Vitamin E deficiency decreases long-chain PUFA in zebrafish (Danio rerio).
.
J Nutr. 141(12):2113-8.
Receptors, LDL
Lytle KA
,
Wong CP
,
Jump DB
. 2017.
Docosahexaenoic acid blocks progression of western diet-induced nonalcoholic steatohepatitis in obese Ldlr-/- mice.
.
PLoS One. 12(4):e0173376.
Depner CM
,
Traber MG
,
Bobe G
,
Kensicki E
,
Bohren KM
,
Milne G
,
Jump DB
. 2013.
A metabolomic analysis of omega-3 fatty acid-mediated attenuation of western diet-induced nonalcoholic steatohepatitis in LDLR-/- mice.
.
PLoS One. 8(12):e83756.
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