Found 909 results
Author [ Keyword(Desc)] Title Type Year
Filters: Author is Dashwood, Roderick H  [Clear All Filters]
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Cell Proliferation
Nian H, Delage B, Pinto JT, Dashwood RH.  2008.  Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter.. Carcinogenesis. 29(9):1816-24.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Wang R, Chen Y-S, Dashwood W-M, Li Q, Löhr CV, Fischer K, Ho E, Williams DE, Dashwood RH.  2017.  Divergent roles of p120-catenin isoforms linked to altered cell viability, proliferation, and invasiveness in carcinogen-induced rat skin tumors.. Mol Carcinog. 56(7):1733-1742.
Larsen CA, Dashwood RH.  2010.  (-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells.. Arch Biochem Biophys. 501(1):52-7.
Cell Survival
Larsen CA, Dashwood RH.  2010.  (-)-Epigallocatechin-3-gallate inhibits Met signaling, proliferation, and invasiveness in human colon cancer cells.. Arch Biochem Biophys. 501(1):52-7.
Wang R, Kang Y, Löhr CV, Fischer KA, C Bradford S, Johnson G, Dashwood WMohaiza, Williams DE, Ho E, Dashwood RH.  2016.  Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.. Cancer Lett. 381(2):341-8.
Cell Transformation, Neoplastic
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Johnson GS, Li J, Beaver LM, W Dashwood M, Sun D, Rajendran P, Williams DE, Ho E, Dashwood RH.  2017.  A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a coactivator of NQO1 in sulforaphane-treated colon cancer cells.. Mol Nutr Food Res. 61(4)
Li Q, Löhr CV, Dashwood RH.  2009.  Activator protein 2alpha suppresses intestinal tumorigenesis in the Apc(min) mouse.. Cancer Lett. 283(1):36-42.
Cells, Cultured
Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, E Houseman A, Williams DE, Dashwood RH, Ho E.  2014.  Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.. PLoS One. 9(1):e86787.
Chemoprevention
Dashwood RH.  2003.  Use of transgenic and mutant animal models in the study of heterocyclic amine-induced mutagenesis and carcinogenesis.. J Biochem Mol Biol. 36(1):35-42.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Chlorophyll
Simonich MT, Egner PA, Roebuck BD, Orner GA, Jubert C, Pereira C, Groopman JD, Kensler TW, Dashwood RH, Williams DE et al..  2007.  Natural chlorophyll inhibits aflatoxin B1-induced multi-organ carcinogenesis in the rat.. Carcinogenesis. 28(6):1294-302.
McQuistan TJ, Simonich MT, M Pratt M, Pereira CB, Hendricks JD, Dashwood RH, Williams DE, Bailey GS.  2012.  Cancer chemoprevention by dietary chlorophylls: a 12,000-animal dose-dose matrix biomarker and tumor study.. Food Chem Toxicol. 50(2):341-52.
Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.
Simonich MT, McQuistan T, Jubert C, Pereira C, Hendricks JD, Schimerlik M, Zhu B, Dashwood RH, Williams DE, Bailey GS.  2008.  Low-dose dietary chlorophyll inhibits multi-organ carcinogenesis in the rainbow trout.. Food Chem Toxicol. 46(3):1014-24.
Chlorophyllides
G Díaz D, Li Q, Dashwood RH.  2003.  Caspase-8 and apoptosis-inducing factor mediate a cytochrome c-independent pathway of apoptosis in human colon cancer cells induced by the dietary phytochemical chlorophyllin.. Cancer Res. 63(6):1254-61.
Chimploy K, G Díaz D, Li Q, Carter O, Dashwood W-M, Mathews CK, Williams DE, Bailey GS, Dashwood RH.  2009.  E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin.. Int J Cancer. 125(9):2086-94.
Blum CA, Xu M, Orner GA, G Díaz D, Li Q, Dashwood WMohaiza, Bailey GS, Dashwood RH.  2003.  Promotion versus suppression of rat colon carcinogenesis by chlorophyllin and chlorophyll: modulation of apoptosis, cell proliferation, and beta-catenin/Tcf signaling.. Mutat Res. 523-524:217-23.
Carter O, Bailey GS, Dashwood RH.  2004.  The dietary phytochemical chlorophyllin alters E-cadherin and beta-catenin expression in human colon cancer cells.. J Nutr. 134(12 Suppl):3441S-3444S.
Wang R, W Dashwood M, Bailey GS, Williams DE, Dashwood RH.  2006.  Tumors from rats given 1,2-dimethylhydrazine plus chlorophyllin or indole-3-carbinol contain transcriptional changes in beta-catenin that are independent of beta-catenin mutation status.. Mutat Res. 601(1-2):11-8.
Chromatin
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Chromatin Assembly and Disassembly
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.

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