Found 517 results
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Gene Expression Regulation, Neoplastic
Wang R, Kang Y, Löhr CV, Fischer KA, C Bradford S, Johnson G, Dashwood WMohaiza, Williams DE, Ho E, Dashwood RH.  2016.  Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer.. Cancer Lett. 381(2):341-8.
Beaver LM, Kuintzle R, Buchanan A, Wiley MW, Glasser ST, Wong CP, Johnson GS, Chang JH, Löhr CV, Williams DE et al..  2017.  Long noncoding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer.. J Nutr Biochem. 42:72-83.
Parasramka MA, W Dashwood M, Wang R, Abdelli A, Bailey GS, Williams DE, Ho E, Dashwood RH.  2012.  MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach.. Mol Nutr Food Res. 56(8):1259-69.
Madeen EP, Löhr CV, You H, Siddens LK, Krueger SK, Dashwood RH, Gonzalez FJ, Baird WM, Ho E, Bramer L et al..  2017.  Dibenzo[def,p]chrysene transplacental carcinogenesis in wild-type, Cyp1b1 knockout, and CYP1B1 humanized mice.. Mol Carcinog. 56(1):163-171.
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Gene Silencing
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Genes, APC
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Genomic Instability
Palomera-Sanchez Z, Watson GW, Wong CP, Beaver LM, Williams DE, Dashwood RH, Ho E.  2017.  The phytochemical 3,3'-diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells.. J Nutr Biochem. 47:113-119.
Gliosis
Loza AMárquez, Elias V, Wong CP, Ho E, Bermudez M, Magnusson KR.  2017.  Effects of ibuprofen on cognition and NMDA receptor subunit expression across aging.. Neuroscience. 344:276-292.
HCT116 Cells
Wang R, Löhr CV, Fischer K, W Dashwood M, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH.  2013.  Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer.. Int J Cancer. 132(5):1004-12.
Histone Deacetylase 2
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Histone Deacetylase 6
Watson GW, Wickramasekara S, Fang Y, Maier CS, Williams DE, Dashwood RH, Perez VI, Ho E.  2016.  HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells.. Exp Biol Med (Maywood). 241(11):1177-85.
Histone Deacetylase Inhibitors
Myzak MC, Ho E, Dashwood RH.  2006.  Dietary agents as histone deacetylase inhibitors.. Mol Carcinog. 45(6):443-6.
Myzak MC, W Dashwood M, Orner GA, Ho E, Dashwood RH.  2006.  Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc-minus mice.. FASEB J. 20(3):506-8.
Dashwood RH, Ho E.  2008.  Dietary agents as histone deacetylase inhibitors: sulforaphane and structurally related isothiocyanates.. Nutr Rev. 66 Suppl 1:S36-8.
Nian H, Delage B, Ho E, Dashwood RH.  2009.  Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.. Environ Mol Mutagen. 50(3):213-21.
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.  2006.  Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.. Carcinogenesis. 27(4):811-9.
Abbas A, J Hall A, Patterson WL, Ho E, Hsu A, Al-Mulla F, Georgel PT.  2016.  Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.. Biochem Cell Biol. 94(1):71-81.
Myzak MC, Tong P, Dashwood W-M, Dashwood RH, Ho E.  2007.  Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects.. Exp Biol Med (Maywood). 232(2):227-34.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.
Rajendran P, Kidane AI, Yu T-W, Dashwood W-M, Bisson WH, Löhr CV, Ho E, Williams DE, Dashwood RH.  2013.  HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates.. Epigenetics. 8(6):612-23.
Histone Deacetylases
Rajendran P, Williams DE, Ho E, Dashwood RH.  2011.  Metabolism as a key to histone deacetylase inhibition.. Crit Rev Biochem Mol Biol. 46(3):181-99.
Beaver LM, Yu T-W, Sokolowski EI, Williams DE, Dashwood RH, Ho E.  2012.  3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.. Toxicol Appl Pharmacol. 263(3):345-51.

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