Cancer Prevention and Intervention (CPI) Core Laboratory

The CPI Core Laboratory provides genetic toxicology testing services to help investigators identify dietary compounds with chemoprotective properties and to elucidate their inhibitory mechanism(s). Techniques include the Salmonella mutagenicity assay (Ames test), single-cell gel electrophoresis assay (Comet assay), micronucleus assay, and histone deacetylase (HDAC) assay.

Please contact Dr. David Yu, CPI Core Lab Manager (david.yu@oregonstate.edu or 541-737-5082).

Oxidative/Nitrative Stress Core Laboratory (ONSL)

The ONSL has several high-performance liquid chromatographs (HPLCs) coupled to UV, fluorescence, electrochemical, and single- and triple-quadrupole mass spectrometer detectors for state-of-the-art chemical analysis of biomarkers, antioxidants, and drug metabolites. ONSL also has several solid-phase extraction robots for sample preparation. Standard analyses include F2-isoprostanes, markers of lipid peroxidation, vitamins C, E, and D, and metabolomics, but custom-designed assays can be performed.

Please contact Jaewoo Choi, ONSL Manager (jaewoo.choi@oregonstate.edu or 541-737-9376).

Healthy Aging Core Laboratory

The Healthy Aging Core Laboratory is currently under development. It will offer a new service to test the efficacy of vitamins, phytochemicals, and micronutrients to prolong health into advanced old age, using turquoise killifish (Nothobranchius furzeri, GRZ strain) as a model of vertebrate aging. Researchers collaborating with the HAP Core Lab will be able to measure a variety of endpoints in conjunction with the ONSL and CCP Core Laboratories.

Please contact Kate Shay for further information (kate.shay@oregonstate.edu).

Food Composition Laboratory

The Food Composition Laboratory provides chemical analyses of food composition and nutritional factors. We provide analyses of food, feed, or dietary supplement samples for vitamins, phytochemicals, and other compositional factors.

Please contact Bob Durst (bob.durst@oregonstate.edu or 541-737-6490).