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Linus Pauling Institute
Micronutrient Research for Optimum Health

Key feature of immune system survived in humans, other primates for 60 million years


A new study has concluded that one key part of the immune system, the ability of vitamin D to regulate antibacterial proteins, is so important that is has been conserved through almost 60 million years of evolution.

  • Determine the function and role of vitamins and essential minerals (micronutrients) and chemicals from plants (phytochemicals) in promoting optimum health and preventing or treating disease
  • Determine the role of oxidative stress and inflammation in human health and disease, and the protective effects of dietary factors with anti-oxidant or anti-inflammatory properties
  • Help people everywhere achieve a healthy and productive life, full of vitality, with minimal suffering, and free of cancer and other debilitating diseases

Major areas of research include cardiovascular and metabolic diseases, cancer, aging, immune function, and neurodegenerative diseases. Specific research projects address:

  • Inflammation, lipoic acid, and essential metals in atherosclerosis
  • Metabolism and health effects of dietary flavonoids
  • Vitamin E metabolism and biological functions
  • Oxidative and environmental stress in Lou Gehrig's, Parkinson's, and Alzheimer's disease
  • Stress response, lipoic acid, and mitochondrial dysfunction in aging
  • Cancer chemoprotection by phytochemicals in tea and vegetables
  • Transplacental cancer chemoprotection
  • Zinc and antioxidants in prostate cancer, immune function, and neurodegeneration
  • Novel biological functions of vitamin C
  • Antioxidants and gene expression in diabetes
  • Dietary fats, and carbohydrate and lipid metabolism
  • Vitamin D in immune function and aging

The Linus Pauling Institute relies heavily on public support to fulfill its mission. We invite you to consider the opportunities for giving to the Institute.