- Determine the role of micronutrients (vitamins and essential minerals), phytochemicals (chemicals from plants), and dietary supplements in extending healthy lifespan (healthspan) and preventing or treating age-associated diseases, including cancer and cardiovascular, metabolic, and neurodegenerative diseases
- Examine the role of oxidative stress and inflammation in human health and disease, and the protective effects of dietary antioxidant and anti-inflammatory factors
- Help people everywhere achieve a healthy and productive life, full of vitality, with minimal suffering, and free of cancer and other debilitating diseases
Major areas of research include cardiovascular and metabolic diseases, cancer, aging, immune function, and neurodegenerative diseases. Specific research projects address:
Dr. Dashwood is awarded Endowed Helen P. Rumbel Professorship for Cancer Prevention.
- Inflammation, lipoic acid, and essential metals in atherosclerosis
- Metabolism and health effects of dietary flavonoids
- Vitamin E metabolism and biological functions
- Oxidative and environmental stress in Lou Gehrig's, Parkinson's, and Alzheimer's disease
- Stress response, lipoic acid, and mitochondrial dysfunction in aging
- Genetic and epigenetic approaches to cancer chemoprotection by dietary phytochemicals, such as sulforaphane, butyrate, and organoselenium compounds
- Transplacental cancer chemoprotection
- Zinc and antioxidants in prostate cancer, immune function, and neurodegeneration
- Novel biological functions of vitamin C
- Antioxidants and gene expression in diabetes
- Dietary fats, and carbohydrate and lipid metabolism
- Vitamin D in immune function and aging
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