Former Director, Linus Pauling Institute
University Distinguished Professor Emeritus, Department of Biochemistry and Biophysics
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Research Interests
After Dr. Balz Frei retired as Director of the Linus Pauling Institute in 2016, he chose not to maintain an active research program. Inquires can be sent to his email address.
Featured Publications
Li C, Zhang WJ, Choi J, Frei B. (2016) Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase. Redox Biol. 9:220-228. doi: 10.1016/j.redox.2016.08.012.
Li C, Zhang WJ, Frei B. (2016) Quercetin inhibits LPS-induced adhesion molecule expression and oxidant production in human aortic endothelial cells by p38-mediated Nrf2 activation and antioxidant enzyme induction. Redox Biol. 9:104-113. doi: 10.1016/j.redox.2016.06.006.
McEvoy CT, Schilling D, Clay N, Jackson K, Go MD, Spitale P, Bunten C, Leiva M, Gonzales D, Hollister-Smith J, Durand M, Frei B, Buist AS, Peters D, Morris CD, Spindel ER. (2014) Vitamin C supplementation for pregnant smoking women and pulmonary function in their newborn infants: a randomized clinical trial. JAMA. 311(20):2074-2082. doi: 10.1001/jama.2014.5217.
Michels AJ, Frei B. (2013) Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research. Nutrients. 5(12):5161-5192. doi: 10.3390/nu5125161.