Richard B. van Breemen, PhD

Endowed Chair and Director, Linus Pauling Institute
Professor of Medicinal Chemistry, Department of Pharmaceutical Sciences, College of Pharmacy

Contact Information:
305 Linus Pauling Science Center
541-737-5078 / 541-737-5077 (fax)
richard.vanbreemen@oregonstate.edu

Research Interests

Cancer prevention by dietary antioxidants, and prostate cancer prevention by the carotenoid lycopene. Mass spectrometry-based pharmacological screening of natural products and combinatorial libraries for drug discovery, and high throughput screening to assess drug metabolism, toxicity and bioavailibility.

Recent Publications 

  • Kondratyuk TP, Adrian JA, Wright BJ, Park EJ, van Breemen RB, Morris KR, Pezzuto JM. "Evidence supporting the conceptual framework of cancer chemoprevention in canines.". Scientific reports. 2016;6:26500. doi:10.1038/srep26500.
  • Hauck ZZ, Feinstein DL, van Breemen RB. "LC-MS-MS Analysis of Brodifacoum Isomers in Rat Tissue.". Journal of analytical toxicology. 2016;40(4):304-9. doi:10.1093/jat/bkw008.
  • Zhou Q, Chen T, Zhang W, Bozkanat M, Li Y, Xiao L, van Breemen RB, Christman JW, Sznajder JI, Zhou G. "Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.". American journal of respiratory cell and molecular biology. 2016;54(5):728-39. doi:10.1165/rcmb.2015-0111OC.
  • Stahlhut RW, van Breemen RB, Gerona RR, Taylor JA, Welshons WV, Vom Saal FS. "Comment on "Optimal Exposure Biomarkers for Nonpersistent Chemicals in Environmental Epidemiology".". Environmental health perspectives. 2016;124(4):A66. doi:10.1289/ehp.1511057.
  • Imai A, Lankin DC, Nikolić D, Ahn S, van Breemen RB, Farnsworth NR, McAlpine JB, Chen S, Pauli GF. "Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa.". Journal of natural products. 2016;79(3):541-54. doi:10.1021/acs.jnatprod.5b00927.
  • Kataria Y, Deaton RJ, Enk E, Jin M, Petrauskaite M, Dong L, Goldenberg JR, Cotler SJ, Jensen DM, van Breemen RB, Gann PH. "Retinoid and carotenoid status in serum and liver among patients at high-risk for liver cancer.". BMC gastroenterology. 2016;16:30. doi:10.1186/s12876-016-0432-5.
  • Newsome AG, Li Y, van Breemen RB. "Improved Quantification of Free and Ester-Bound Gallic Acid in Foods and Beverages by UHPLC-MS/MS.". Journal of agricultural and food chemistry. 2016;64(6):1326-34. doi:10.1021/acs.jafc.5b04966.
  • Hauck ZZ, Huang KG, Li G, van Breemen RB. "Determination of bisphenol A-glucuronide in human urine using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.". Rapid communications in mass spectrometry : RCM. 2016;30(3):400-6. doi:10.1002/rcm.7450.